Human Physiology

, Volume 41, Issue 3, pp 289–295 | Cite as

Velocity of regional blood flow and blood flow in the middle cerebral artery in surgical leg lengthening in patients with congenital and acquired limb shortening

  • V. A. SchurovEmail author
  • A. V. Popkov


A comparative study of the changes in blood flow velocity in the popliteal artery, arteries of the regenerated bone and the cerebral arteries was performed in 45 patients with congenital and acquired diseases of the limbs at different stages of the Ilizarov surgical lengthening of leg shortened by 3–15 cm. An increase in the regional blood flow was detected in all patients during periods of distraction and fixation. An increase in the blood flow velocity in the middle cerebral artery on the contralateral side by 25% was found only in patients of the first adult age with acquired limb shortening. Based on the results of analyzing the reaction of cerebral arteries in functional test with an additional muscle work, we assumed that the absence of response in congenital diseases is caused by a relative excess of somatic afferentation as a result of the morphological and functional immaturity of the brain regulatory systems.


limb lengthening Ilizarov method middle cerebral artery 


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  1. 1.
    Shchurov, V.A. and Grebeniuk, L.A., Dependence of the biomechanical properties of the lower leg muscles on their length in patients with diseases of the locomotor apparatus, Fiziol. Chel., 1994, vol. 20, no. 2, p. 105.Google Scholar
  2. 2.
    Popkov, A.V., Aranovich, A.M., and Popkov, D.A., Features of surgical treatment of children with congenital fibular hemimelia, Genii Ortopedii, 2013, no. 1, p. 55.Google Scholar
  3. 3.
    Popkov, A.V. and Popkov, D.A., The details of functional recovery after surgical treatment of children with congenital shortening of lower limbs, Genii Ortopedii, 2008, no. 1, p. 19.Google Scholar
  4. 4.
    Lindsey, C., Makarov, M., Shoemaker, S., Birch, J.G., Buschang, P.H., Cherkashin, A.M., Welch, R.D., and Samchukov, M.L., The effect of the amount of limb lengthening on skeletal muscle, Clin. Orthop. Relat. Res., 2002, vol. 402, p. 278.CrossRefGoogle Scholar
  5. 5.
    Vargas Barreto, B., Caton, J., Merabet, Z., Panisset, J.C., and Pracros, J.P., Complications of Ilizarov leg lengthening: a comparative study between patients with leg length discrepancy and short stature, Int. Orthopaed., 2007, vol. 31, no. 5, p. 587.CrossRefGoogle Scholar
  6. 6.
    Schurov, V.A., Matsukatov, F.A., and Darvin, E.O., Effect of humerus fractures on blood flow velocity in the upper limb and brain, J. Orthopaed. Trauma Surgery Related Res. Poland, 2014, nos. 34–35, p. 52.Google Scholar
  7. 7.
    Shchurov, V.A., Dolganova, T.I., Shchurova, E.N., and Gorbacheva, L.Yu., Analysis of the factors determining the volumetric blood flow velocity in the Ilizarov treatment of diseases of the limbs, Travmatol. Ortoped. Rossii, 1994, no. 2, p. 91.Google Scholar
  8. 8.
    Shchurov, V.A., Butorina, N.I., and Shchurov, I.V., High-frequency Doppler ultrasound of bone regenerate, Regionar. Krovoobr. Mikrotsirk., 2007, vol. 1, no. 21, p. 145.Google Scholar
  9. 9.
    Shchurov, V.A., RF Patent 2029536, Byull. Izobret., 1995, no. 6.Google Scholar
  10. 10.
    Blake, C., Codd, M.B., O’Meara, Y.M., The short form 36 (SF-36) health survey: normative data for the Irish population, Irish J. Med. Sci., 2000, vol. 169, no. 3, p. 195.CrossRefGoogle Scholar
  11. 11.
    Shchurov, V.A. and Kuchin, R.V., Effect of shin lengthening and regular exercise on limb arteries, Human Physiol., 2001, vol. 27, no. 3, p. 322.CrossRefGoogle Scholar
  12. 12.
    Shchurov, V.A. and Berg, M.D., The impact of injuries and diseases of the limbs and brain on their blood supply and the relationship of these indicators, Fundam. Issled., 2013, no. 2, p. 211.Google Scholar
  13. 13.
    Baumbach, G.L. and Heistad, D.D., Effects of sympathetic stimulation and changes in arterial pressure on segmental resistance of cerebral vessels in rabbits and cats, Circ. Res., 1983, vol. 52, no. 5, p. 527.CrossRefGoogle Scholar
  14. 14.
    Madsen, P.L., Sperling, B.K., Warming, T., Schmidt, J.F., Secher, N.H., Wildschiødtz, G., Holm, S., and Lassen, N.A., Middle cerebral artery blood velocity and cerebral blood flow and O2 uptake during dynamic exercise, J. Appl. Physiol., 1993, vol. 74, no. 1, p. 245.CrossRefGoogle Scholar
  15. 15.
    Moraine, J.J., Lamotte, M., Berré, J., Niset, G., Leduc, A., and Naeije, R., Relationship of middle cerebral artery blood flow velocity to intensity during dynamic exercise in normal subjects, Eur. J. Appl. Physiol. Occup. Physiol., 1993, vol. 67, no. 1, p. 35.CrossRefGoogle Scholar
  16. 16.
    Bys, M., Brown, C.M., Marthol, H., Franta, R., and Hilz, M.J., Dynamic cerebral autoregulation remains stable during physical challenge in healthy persons, Am. J. Physiol.: Heart Circ. Physiol., 2003, vol. 285, no. 3, p. H1048.Google Scholar
  17. 17.
    Shchurov, V.A., Dolganova, T.I., and Shchurova, E.N., Pulse wave velocity when changing the limb length and regional arterial pressure in subjects of different ages, Fiziol. Chel., 1993, vol. 19, no. 4, p. 64.Google Scholar
  18. 18.
    Lorens, I.H., Kolbitsch, C., Hinteregger, M., Bauer, P., Spiegel, M., Luger, T.J., Schmidauer, C., Streif, W., Pfeiffer, K.P., and Benzer, A., Remifentanil and nitrous oxide reduce changes in cerebral blood flow velocity in the middle cerebral artery caused by pain, Brit. J. Anaesth., 2003, vol. 90, no. 3, p. 296.CrossRefGoogle Scholar
  19. 19.
    Micieli, G., Tassorelli, C., Bosone, D., Cavallini, A., Viotti, E., and Nappi, G., Intracerebral vascular changes induced by cold pressor test: a model of sympathetic activation, Neurol. Res., 1994, vol. 16, no. 3, p. 163.CrossRefGoogle Scholar
  20. 20.
    Poulin, M.J., Syed, R.J., and Robbins, P.A., Assessments of flow by transcranial Doppler ultrasound in the middle cerebral artery during exercise in humans, J. Appl. Physiol., 1999, vol. 86, no. 5, p. 1632.CrossRefGoogle Scholar
  21. 21.
    Kulikov, V.P., Gatal’skii, K.K., Doronina, N.L., et al., Hemodynamics reaction to physical stress of moderate intensity, Ros. Fiziol. Zh. im. I.M. Sechenova, 2007, no. 2, p. 161.Google Scholar
  22. 22.
    Olson, T.P., Tracy, J., and Dengel, D.R., Relationship between ventilatory threshold and cerebral blood flow during maximal exercise in humans, Open Sports Med. J., 2009, vol. 3, p. 9.CrossRefGoogle Scholar
  23. 23.
    Hellebrandt, F.A., Cross education: ipsilateral and contralateral effects of unimanual training, J. Appl. Physiol., 1951, vol. 4, p. 136.CrossRefGoogle Scholar
  24. 24.
    Svensson, P., Minoshima, S., Beydoun, A., Morrow, T.J., and Casey, K.L., Cerebral processing of acute skin and muscle pain in humans, J. Neurophysiol., 1997, vol. 78, no. 1, p. 450.CrossRefGoogle Scholar
  25. 25.
    Casey, K.L., Minoshima, S., Morrow, T.J., and Koeppe, R.A., Comparison of human cerebral activation pattern during cutaneous warmth, heat pain, and deep cold pain, J. Neurophysiol., 1996, vol. 76, no. 1, p. 571.CrossRefGoogle Scholar
  26. 26.
    Sorond, F.A., Galica, A., Serrador, J.M., Kiely, D.K., Iloputaife, I., Cupples, L.A., and Lipsitz, L.A., Cerebrovascular hemodynamics, gait, and falls in an elderly population MOBILIZE Boston Study, Neurology, 2010, vol. 74, no. 20, p. 1627.CrossRefGoogle Scholar
  27. 27.
    Ilizarov, G.A., General biological property of tissues to respond to dosed distension by growth and regeneration (the Ilizarov effect), Diploma no. 365, Byull. Izobret., 1989, no. 15.Google Scholar
  28. 28.
    Sechenov, I.M., The elements of thought, in Izbrannye trudy I.M. Sechenova, I.P. Pavlova, N.E. Vvedenskogo (Selected Papers by I.M. Sechenov, I.P. Pavlov, and N.E. Vvedenskii), Moscow: Medgiz, 1952.Google Scholar
  29. 29.
    Mogendovich, M.R. and Tyemkin, I.B., Physiological Bases of Therapeutic Physical Culture, Izhevsk: Udmurtiya, 1975.Google Scholar
  30. 30.
    Ilizarov, G.A., Transosseous Osteosynthesis: Theoretical and Clinical Aspects of the Regeneration Growth of Tissue, Berlin-Heidelberg: Springer, 1992.CrossRefGoogle Scholar

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© Pleiades Publishing, Inc. 2015

Authors and Affiliations

  1. 1.Russian Ilizarov Scientific Center “Restorative Traumatology and Orthopaedics” of the RF Ministry of HealthKurganRussia

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