Human Physiology

, Volume 39, Issue 5, pp 535–539

Detection of renal and urinary tract proteins in urine before and after space flight

  • L. Kh. Pastushkova
  • K. S. Kireev
  • A. S. Kononikhin
  • E. S. Tiys
  • I. A. Popov
  • I. V. Dobrokhotov
  • V. A. Ivanisenko
  • V. B. Noskov
  • I. M. Larina
  • E. N. Nikolaev
Article

DOI: 10.1134/S0362119713050125

Cite this article as:
Pastushkova, L.K., Kireev, K.S., Kononikhin, A.S. et al. Hum Physiol (2013) 39: 535. doi:10.1134/S0362119713050125

Abstract

The urine protein composition (proteome) of healthy humans was analyzed using proteomic techniques to obtain data under normal physiological conditions and after six-month space flights. It was shown that, after long space flights, specific minor proteins are revealed in cosmonauts’ urine that can be identified as proteins coming from kidneys and urinary tracts.

Keywords

urine proteome space flight healthy humans water-salt balance 

Copyright information

© Pleiades Publishing, Inc. 2013

Authors and Affiliations

  • L. Kh. Pastushkova
    • 1
  • K. S. Kireev
    • 2
  • A. S. Kononikhin
    • 3
    • 4
  • E. S. Tiys
    • 5
  • I. A. Popov
    • 3
    • 4
  • I. V. Dobrokhotov
    • 1
  • V. A. Ivanisenko
    • 5
  • V. B. Noskov
    • 1
  • I. M. Larina
    • 1
  • E. N. Nikolaev
    • 3
    • 4
  1. 1.Institute of Biomedical ProblemsRussian Academy of SciencesMoscowRussia
  2. 2.Gagarin Cosmonaut Training CenterMoscow oblastRussia
  3. 3.Emanuel Institute of Biochemical PhysicsRussian Academy of SciencesMoscowRussia
  4. 4.Institute of Energy Problems of Chemical PhysicsRussian Academy of SciencesMoscowRussia
  5. 5.Institute of Cytology and GeneticsRussian Academy of SciencesNovosibirskRussia

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