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Russian Journal of Physical Chemistry A

, Volume 93, Issue 13, pp 2656–2660 | Cite as

The Study of Mg(II) Ion Influence on Catechol Autoxidation in Weakly Alkaline Aqueous Solution

  • G. M. NikolićEmail author
  • S. C. Živanović
  • N. S. Krstić
  • M. G. Nikolić
PHYSICAL CHEMISTRY OF SOLUTIONS

Abstract

High performance liquid chromatography with diode array detection (HPLC-DAD) and electron spin resonance (ESR) spectroscopy were used to study Mg(II) ion influence on the autoxidation of catechol in weakly alkaline solution. The presence of Mg(II) ions greatly enhanced the catechol autoxidation rate and probably influenced the mechanism of reaction thus enabling formation of reaction products not obtained in the absence of metal ions. Consecutive formation of 1,2-benzoquinone, 2,3-oxanthrenediol, and 2,3-oxanthrenedione with intermediate o-semiquinone anion radicals during the initial stages of catechol autoxidation was suggested based on the detailed analysis of experimental HPLC-DAD and ESR data. The results of this study may help in better understanding of autoxidation of some biologically important catecholic molecules in real systems, where Mg(II) ions are ubiquitously present. Because of the possible toxicity of simple quinone molecules, it is important that the formation of relatively stable quinoid autoxidation products were detected in this study.

Keywords:

catechol autoxidation magnesium ion 

Notes

ACKNOWLEDGMENTS

This work was partially supported by the Ministry for Science and Technological Development of the Republic of Serbia (grant no. 172044).

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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • G. M. Nikolić
    • 1
    Email author
  • S. C. Živanović
    • 2
  • N. S. Krstić
    • 3
  • M. G. Nikolić
    • 3
  1. 1.Department of Chemistry, Faculty of Medicine, University of NišNišSerbia
  2. 2.Research Center for Biomedicine, Faculty of Medicine, University of NišNišSerbia
  3. 3.Department of Chemistry, Faculty of Sciences and Mathematics, University of NišNišSerbia

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