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Problems of Information Transmission

, Volume 44, Issue 4, pp 333–351 | Cite as

Gibbs field approach for evolutionary analysis of regulatory signal of gene expression

  • V. A. Lyubetsky
  • E. A. Zhizhina
  • L. I. Rubanov
Large Systems

Abstract

We propose a new approach to modeling a nucleotide sequence evolution subject to constraints on the secondary structure. The approach is based on the problem of optimizing a functional that involves both standard evolution of the primary structure and a condition of secondary structure conservation. We discuss simulation results in the example of evolution in the case of classical attenuation regulation.

Keywords

Secondary Structure Primary Structure Information Transmission Evolutionary Analysis Regulation Site 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2008

Authors and Affiliations

  • V. A. Lyubetsky
    • 1
  • E. A. Zhizhina
    • 1
  • L. I. Rubanov
    • 1
  1. 1.Kharkevich Institute for Information Transmission ProblemsRASMoscowRussia

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