Optics and Spectroscopy

, 107:534 | Cite as

Influence of terahertz laser radiation on the spectral characteristics and functional properties of albumin

  • O. P. Cherkasova
  • V. I. Fedorov
  • E. F. Nemova
  • A. S. Pogodin
Fundamental Problems of Optics—2008: Terahertz Optics and Spectroscopy

Abstract

The exposure of albumin (transport protein of blood serum) to laser radiation with a frequency of 3.6 THz resulted in a change in the intensity of characteristic bands in UV absorption spectra and in circular dichroism spectra. These changes depend on the exposure duration and the laser radiation power and indicate conformational changes in protein molecules.

PACS numbers

87.50.Uj 42.62.Be 

References

  1. 1.
    S. W. Smye, J. M. Chamberlain, A. J. Fitzgerald, and E. Berry, Phys. Med. Biol. 46(9), R101 (2001).CrossRefADSGoogle Scholar
  2. 2.
    N. Laman, Biophys. J. 94, 1010 (2008).CrossRefADSGoogle Scholar
  3. 3.
    V. I. Fedorov and S. S. Popova, Millimetr. Volny Biol. Med., No. 2, 3 (2006).Google Scholar
  4. 4.
    M. N. Komarova and Yu. A. Gryzunov, in Blood Serum Albumin in Clinical Medicine (Géotar, Moscow, 1998), Vol. 2, pp. 28–51 [in Russian].Google Scholar
  5. 5.
    G. E. Dobretsov and Yu. I. Miller, in Blood Serum Albumin in Clinical Medicine (Irius, Moscow, 1994), pp. 11–28 [in Russian].Google Scholar
  6. 6.
    K. V. Shaĭtan, Soros. Obrazovat. Zh., No. 5, 8 (1999).Google Scholar
  7. 7.
    V. M. Govorun, V. E. Tretiakov, N. N. Tulyakov, V. B. Fleurov, A. I. Demin, A. Yu. Volkov, V. Batanov, and A. B. Kapitanov, Int. J. Infrared and Millimeter Waves 12, 1469 (1991).CrossRefADSGoogle Scholar
  8. 8.
    V. F. Zakhar’yash, V. M. Klement’ev, S. A. Malinin, et al., Prib. Tekh. Eksp., No. 1, 130 (1996).Google Scholar
  9. 9.
    A. M. Romeu, E. E. Martino, and A. O. M. Stoppani, Biochim. Biophys. Acta 439, 174 (1976).Google Scholar
  10. 10.
    A. Papadopoulou, R. J. Green, and R. A. Frazier, J. Agric. Food Chem. 53(1), 158 (2005).CrossRefGoogle Scholar
  11. 11.
    Circular Dichroism and Conformational Analysis of Biomolecules, Ed. by G. D. Fasman (Plenum, New York, 1996), p. 250.Google Scholar

Copyright information

© Pleiades Publishing, Ltd. 2009

Authors and Affiliations

  • O. P. Cherkasova
    • 1
  • V. I. Fedorov
    • 1
  • E. F. Nemova
    • 1
  • A. S. Pogodin
    • 1
  1. 1.Institute of Laser PhysicsSiberian Branch of the Russian Academy of SciencesNovosibirskRussia

Personalised recommendations