Molecular Biology

, Volume 53, Issue 4, pp 560–570 | Cite as

Structural and Functional Organization of the Mitochondrial DNA Control Region in the Woolly Mammoth (Mammuthus primigenius)

  • I. V. KornienkoEmail author
  • T. G. Faleeva
  • N. V. Oreshkova
  • S. E. Grigoriev
  • L. V. Grigorieva
  • Yu. A. Putintseva
  • K. V. Krutovsky


The woolly mammoth mitochondrial genome (including the Malolyakhovsky mammoth) has been previously sequenced, followed by the annotation of all its genes (MF770243). In this study, based on the Malolyakhovsky mammoth, we describe for the first time the sites of functional significance in the control region of the woolly mammoth mitogenome.


ancient DNA mitochondrial DNA control region woolly mammoth paleogenetics 



The study was carried out as part of the state contract of the Southern Scientific Center of the Russian Academy of Sciences, grant no. 01201363186.


The authors declare that they have no conflict of interest. This article does not contain any studies involving animals or human participants performed by any of the authors.


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Copyright information

© Pleiades Publishing, Inc. 2019

Authors and Affiliations

  • I. V. Kornienko
    • 1
    • 2
    Email author
  • T. G. Faleeva
    • 2
    • 3
  • N. V. Oreshkova
    • 4
    • 5
    • 6
  • S. E. Grigoriev
    • 7
  • L. V. Grigorieva
    • 8
  • Yu. A. Putintseva
    • 5
  • K. V. Krutovsky
    • 5
    • 9
    • 10
    • 11
  1. 1.Southern Scientific Centre, Russian Academy of SciencesRostov-on-DonRussia
  2. 2.Ivanovsky Academy of Biology and Biotechnology, Southern Federal UniversityRostov-on-DonRussia
  3. 3.Branch No. 2 of the 111th Main State Center of Medical Forensic and Criminalistic Examinations, Ministry of Defense of the Russian FederationRostov-on-DonRussia
  4. 4.Sukachev Institute of Forest, Siberian Branch, Russian Academy of SciencesKrasnoyarskRussia
  5. 5.Genome Research and Education Center, Siberian Federal UniversityKrasnoyarskRussia
  6. 6.Laboratory of Genomic Research and Biotechnology, Federal Research Center Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of SciencesKrasnoyarskRussia
  7. 7.Lazarev Mammoth Museum, Institute of Applied Ecology of the North, North-Eastern Federal UniversityYakutskRussia
  8. 8.International Common Use Center Molecular Paleontology, North-Eastern Federal UniversityYakutskRussia
  9. 9.Department of Forest Genetics and Forest Tree Breeding, Georg-August University of GöttingenGöttingenGermany
  10. 10.Vavilov Institute of General Genetics, Russian Academy of SciencesMoscowRussia
  11. 11.Department of Ecosystem Science and Management, Texas A&M UniversityCollege StationUnited States

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