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Effect of Succinic Acid on the Antiradical Properties of 5-Hydroxy-6-Methyluracil


The antiradical activity of the associates of 5-hydroxy-6-methyluracil with succinic acid, whose compositions differed in the succinic acid content, in a model system for the initiated radical chain oxidation of 1,4-dioxane was quantitatively studied. The parameter characterizing the inhibitory activity of the test associates was measured: fk7 = (3.2 ± 0.1) × 104 L mol–1 s–1 (333 K). The antioxidant activities of 5-hydroxy-6-methyluracil and its associates with succinic acid were compared.

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This study was carried out using the equipment of the Chemistry Center for Collective Use.


This work was performed at the Ufa Institute of Chemistry, Russian Academy of Sciences in accordance with a research plan (state registration nos. AAAA-A17-117011910034-8 and AAAA-A19-119011790021-4).

Author information

Correspondence to L. R. Yakupova.

Additional information

Translated by Valentin Makhlyarchuk

Abbreviations: HMU, 5-hydroxy-6-methyluracil; SA, succinic acid; AIBN, 2,2'-azo-bis-isobutyronitrile.

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Yakupova, L.R., Nasibullina, R.A., Gimadieva, A.R. et al. Effect of Succinic Acid on the Antiradical Properties of 5-Hydroxy-6-Methyluracil. Kinet Catal 60, 783–789 (2019).

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  • radical chain oxidation
  • 1,4-dioxane
  • inhibition rate constant
  • 5-hydroxy-6-methyluracil
  • succinic acid