Blood supply as a factor regulating pacemaker activity of the rat uterine horn
- 62 Downloads
The effect of ischemia of the uterine artery supplying blood to the main rhythmogenic ovarian zone of the uterine horn in non-pregnant rats was investigated. Parameters of pacemaker activity of the given locus and all the subsequent pacemaker areas up to the cervix were studied under the influence of ischemia. The greatest changes of the amplitude, frequency and burst duration time of spike activities were recorded in the ovarian end of horn. The uterine corpus and cervical end of horn were less affected by ischemia. However, amplitude of the slow-wave oscillations increased by more than one and a half in these conditions. Data obtained allow us to state about presence of certain connection between the ovarian end of horn and uterine cervix. Morphological studies revealed strong vascularization of the upper part of uterine horn.
Key wordsuterus uterine horn ovarian part cervical part uterine cervix spike activity slow-wave activity
Unable to display preview. Download preview PDF.
- 2.Mancinelli, R., Guariglia, L., Racanicchi, C., Bertuzzi, A., Salinari, S., and Vitelli, R., In vitro Motility of Non-Pregnant Rat Uterine Horns, Quar. J. Exp. Physiol., 1988, vol. 73, pp. 459–469.Google Scholar
- 3.Kazaryan, K.V., Hunanyan, N.G., and Akopyan, R.R., The Characters of Electrophysiological Properties in Various Parts of Uterus and Bordering Area of Rat Uterine Tube, Ross. Fiziol. Zhurn. im. I.M. Sechenova, 2010, vol. 96, no. 10, pp. 981–987.Google Scholar
- 6.Hamilton, W.F., Circulation, vol. 2 (Handbook of Physiology Series, Section 2), 1963, American Physiol. Soc., Bethseda.Google Scholar
- 14.Chilingaryan, A.M., The New Calcium-Adenosine Triphosphate Method for the Detection of Interorgan Microcirculator Way, Dokl. Akad. Nauk Armenii, 1986, vol. 82, no. 1, pp. 66–71.Google Scholar
- 18.Buhimschi, C.S., Saade, G.R., Buhimschi, I.A., Gokdeniz, R., Boyle, M.B., and Garfield, R.E., Effect of Stimulatory and Inhibitory Drugs on Uterine Electrical Activity Measured Noninvasively from the Abdominal Surface of Pregnant Rats, Amer. J. Obstet. Gynecol., 2000, vol. 183, pp. 68–75.Google Scholar