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Inorganic Materials

, Volume 49, Issue 11, pp 1148–1151 | Cite as

Preparation of octacalcium phosphate from calcium carbonate powder

  • A. Yu. Fedotov
  • V. S. KomlevEmail author
  • A. Yu. Teterina
  • V. P. Sirotinkin
  • V. F. Shamrai
  • I. V. Fadeeva
  • S. M. Barinov
Article

Abstract

We have studied a process for the preparation of apatite precursors through calcium carbonate conversion into dicalcium phosphate dihydrate, which is then hydrolyzed to octacalcium phosphate. The process enables the preparation of both phase-pure octacalcium phosphate and calcium phosphate mixtures with variable dicalcium phosphate dihydrate : octacalcium phosphate and hydroxyapatite : octacalcium phosphate ratios.

Keywords

Calcium Carbonate DCPD Octacalcium Phosphate Sodium Acetate Solution Ammonium Dihydrogen Phosphate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bohner, M., Galea, L., and Doebelin, N., Calcium phosphate bone graft substitutes: Failures and hopes, J. Eur.. Ceram. Soc., 2012, vol. 32, pp. 2663–2671.CrossRefGoogle Scholar
  2. 2.
    Barinov, S.M. and Komlev, V.S., Osteoinductive ceramic materials for bone tissue regeneration: Octacalcium phosphate, Materialovedenie, 2009, no. 10, pp. 34–41.Google Scholar
  3. 3.
    Dorozhkin, S.V., Calcium orthophosphates in nature, biology and medicine, Materials, 2009, pp. 399–498.Google Scholar
  4. 4.
    Barrère, F., Blitterswijk, C., and de Groot, K., Bone regeneration: Molecular and cellular interactions with calcium phosphate ceramics, Int. J. Nanomed., 2006, vol. 3, pp. 317–332.Google Scholar
  5. 5.
    Ta, A.C., Granules of brushite and octacalcium phosphate from marble, J. Am. Ceram. Soc., 2011, vol. 94, pp. 3722–3726.CrossRefGoogle Scholar
  6. 6.
    Rau, J.V., Fosca, M., Komlev, V.S., et al., In situ timeresolved studies of octacalcium phosphate and dicalcium phosphate dihydrate in simulated body fluid: Cooperative interactions and nanoapatite crystal growth, Cryst. Growth Des., 2010, vol. 10, pp. 3824–3834.CrossRefGoogle Scholar
  7. 7.
    Rokidi, S., Combes, C., and Koutsoukos, P.G., The calcium phosphate-calcium carbonate system: Growth of octacalcium phosphate on calcium carbonates, Cryst. Growth Des., 2011, vol. 11, pp. 1683–1688.CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  • A. Yu. Fedotov
    • 1
  • V. S. Komlev
    • 1
    Email author
  • A. Yu. Teterina
    • 1
  • V. P. Sirotinkin
    • 1
  • V. F. Shamrai
    • 1
  • I. V. Fadeeva
    • 1
  • S. M. Barinov
    • 1
  1. 1.Baikov Institute of Metallurgy and Materials ScienceRussian Academy of SciencesMoscowRussia

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