Doklady Biological Sciences

, Volume 468, Issue 1, pp 112–114 | Cite as

Semax prevents learning and memory inhibition by heavy metals

  • A. N. Inozemtsev
  • S. B. Bokieva
  • O. V. Karpukhina
  • K. Z. Gumargalieva
  • A. A. Kamensky
  • N. F. Myasoedov
Physiology

Abstract

Separate and joint effect of Semax, ascorbic acid, lead diacetate, and ammonium molybdate on avoidance conditioning in rats was studied. It was established that the heavy metal salts inhibited the avoidance response, and the peptide counteracted this inhibition as strongly as ascorbic acid or to a comparable degree. These findings confirm the antioxidant properties of Semax.

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • A. N. Inozemtsev
    • 1
  • S. B. Bokieva
    • 2
  • O. V. Karpukhina
    • 1
    • 2
  • K. Z. Gumargalieva
    • 3
  • A. A. Kamensky
    • 1
  • N. F. Myasoedov
    • 4
  1. 1.Moscow State UniversityMoscowRussia
  2. 2.Khetagurov North Ossetian State UniversityVladikavkaz, North OssetiaRussia
  3. 3.Semenov Institute of Chemical PhysicsRussian Academy of SciencesMoscowRussia
  4. 4.Institute of Molecular GeneticsRussian Academy of SciencesMoscowRussia

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