, Volume 54, Issue 2, pp 152–155 | Cite as

Mechanism of manganese transport regulation in Brucella involving a long RNA helix

  • A. V. Seliverstov
  • V. A. Lyubetsky
Molecular Biophysics


It has been found that divalent cation transporters of the Nramp family in eukaryotic cell phagosomes and bacteria that parasitize in these cells compete for metals, which is significant for bacterial survival. Long helices were determined by means of our algorithm in the 5′-untranslated region for each mRNA in Brucella. Long helices of quite similar nucleotide composition were found in mRNAs that encode manganese transporters and Ni-dependent glyoxalase I. We suggest that long helices in these regions are involved in the regulation of RNA stability.

Key words

Brucella manganese transport RNA helix 


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Copyright information

© Pleiades Publishing, Ltd. 2009

Authors and Affiliations

  1. 1.Institute for Information Transmission ProblemsRussian Academy of SciencesMoscowRussia

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