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Biochemistry (Moscow)

, Volume 82, Issue 5, pp 565–571 | Cite as

Induction of transposon silencing in the Drosophila germline

  • S. S. Ryazansky
  • A. D. Stolyarenko
  • M. S. Klenov
  • V. A. GvozdevEmail author
Mini-Review

Abstract

In this review we consider the role of the piRNA system in transposable element silencing in the Drosophila melanogaster germline. We focus on new data that demonstrate the mechanisms of initiation of piRNA biogenesis in ovarian germinal cells and the role of Piwi protein in this process, including our own results.

Keywords

transposon Piwi protein piRNA Drosophila small RNAs 

Abbreviations

H3K9me3

histone H3 trimethylated at K9

piRNA

Piwi-interacting RNA

RDC

complex of proteins Rhino, Deadlock, and Cutoff

TE

transposable element

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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  • S. S. Ryazansky
    • 1
  • A. D. Stolyarenko
    • 1
  • M. S. Klenov
    • 1
  • V. A. Gvozdev
    • 1
    Email author
  1. 1.Institute of Molecular GeneticsRussian Academy of SciencesMoscowRussia

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