Biochemistry (Moscow)

, Volume 81, Issue 12, pp 1480–1487 | Cite as

Molecular and cellular interactions between mother and fetus. Pregnancy as a rejuvenating factor

  • V. A. Popkov
  • D. N. Silachev
  • S. S. Jankauskas
  • L. D. Zorova
  • I. B. Pevzner
  • V. A. Babenko
  • E. Y. Plotnikov
  • D. B. Zorov
Phenoptosis (Special Issue) Review


Aging is associated with a decline of various body functions, including ability to regenerate. Over recent decades, it has been demonstrated that some of these changes could be reversed in response to factors originating from a young organism, for example, fetal stem cells or “young blood” in models of heterochronic parabiosis. Pregnancy might be considered as parabiotic model of the interaction between two organisms of different age. In this work, we analyzed and summarized data on the effects of pregnancy on the maternal organism that confirm the hypothesis that pregnancy rejuvenates the mother’s organism or slows its aging.

Key words

pregnancy rejuvenation aging 


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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • V. A. Popkov
    • 1
    • 2
  • D. N. Silachev
    • 1
  • S. S. Jankauskas
    • 1
  • L. D. Zorova
    • 3
  • I. B. Pevzner
    • 1
  • V. A. Babenko
    • 2
    • 4
  • E. Y. Plotnikov
    • 1
  • D. B. Zorov
    • 1
  1. 1.Lomonosov Moscow State University, Belozersky Institute of Physico-Chemical BiologyMoscowRussia
  2. 2.Lomonosov Moscow State University, Faculty of Bioengineering and BioinformaticsMoscowRussia
  3. 3.Lomonosov Moscow State University, International Laser CenterMoscowRussia
  4. 4.Research Center of Obstetrics, Gynecology and PerinatologyMoscowRussia

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