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Biochemistry (Moscow)

, Volume 81, Issue 3, pp 284–288 | Cite as

Mathematical model of self-oscillations of activity of Kai proteins

  • Sh. K. BayramovEmail author
Article

Abstract

A non-autocatalytic mathematical model of self-oscillations in vitro in solutions of cyanobacterial Kai proteins (KaiA, KaiB, KaiC) and ATP is suggested. This model describes the process of phosphorylation/dephosphorylation of KaiC protein, which is accelerated by KaiA and inhibited by KaiB. The method of metabolic control analysis is used to show that frequency (period) as well as amplitude of self-oscillations of components of Kai proteins are temperature-compensated.

Key words

biochemical self-oscillations Kai proteins control analysis of frequency control analysis of amplitude 

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  1. 1.Azerbaijan Medical UniversityBakuAzerbaijan

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