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Biochemistry (Moscow)

, Volume 80, Issue 3, pp 323–331 | Cite as

Hybrid structures of polycationic aluminum phthalocyanines and quantum dots

  • E. G. MaksimovEmail author
  • D. A. Gvozdev
  • M. G. Strakhovskaya
  • V. Z. Paschenko
Article

Abstract

Semiconductor nanocrystals (CdSe/ZnS quantum dots, QDs) were used as inorganic focusing antenna, allowing for the enhancement of fluorescence and photosensitizing activity of polycationic aluminum phthalocyanines (PCs). It was found that QDs form stable complexes with PCs in aqueous solutions due to electrostatic interactions. In such hybrid complexes, we observed highly efficient nonradiative energy transfer from QD to PC, leading to a sharp increase in the effective absorption cross section of PC in the absorption bands of the CdSe/ZnS quantum dots. When hybrid complexes are excited within these bands, the intensity of PC fluorescence and the rate of photosensitized singlet oxygen generation increases significantly (up to 500 and 350%, correspondingly) compared to free PC at the same concentration. The observed effect is of interest for modeling primary stages of photosynthesis and increasing photosensitizing activity of dyes used in photodynamic therapy.

Key words

quantum dots aluminum phthalocyanines hybrid systems energy migration reactive oxygen species 

Abbreviations

DPBF

1,3-diphenylisobenzofuran

PCY

aluminum phthalocyanine, where Y is degree of substitute incorporation

QDX

quantum dots with emission maximum X

ROS

reactive oxygen species

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Copyright information

© Pleiades Publishing, Ltd. 2015

Authors and Affiliations

  • E. G. Maksimov
    • 1
    Email author
  • D. A. Gvozdev
    • 1
  • M. G. Strakhovskaya
    • 1
    • 2
  • V. Z. Paschenko
    • 1
  1. 1.Faculty of BiologyLomonosov Moscow State UniversityMoscowRussia
  2. 2.Russian Federal Research Centre of Medical Care and Medical TechnologyMoscowRussia

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