Biochemistry (Moscow)

, Volume 78, Issue 9, pp 1061–1070

Studies that shed new light on aging



I will first discuss how all aging models that assume that the aged cell has irreversibly lost its youthful capabilities through such mechanisms as accumulated dysfunction, accumulated damage, and/or accumulation of toxic byproducts of metabolism have been shown to be incorrect. I will then briefly discuss models of aging and propose an experiment that would distinguish between those models and provide a basis for organismic rejuvenation.

Key words

aging aging mechanisms theories of aging parabiosis cross-age transplantation rejuvenation cellular aging age-dependent transcriptional patterns 


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Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  1. 1.University of MarylandUniversity CollegeMarylandUSA

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