New functions of small nucleolar RNAs
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Small nucleolar RNAs (snoRNAs) are one of the most abundant and well-studied groups of non-coding RNAs. snoRNAs are mostly engaged in processing of rRNA. However, recent data indicate that snoRNAs are also involved in other processes including regulation of alternative splicing, translation and oxidative stress. snoRNAs are also involved in pathogenesis of some hereditary diseases and cancer. Therefore, the range of snoRNAs’ functions is significantly wider than it has been assumed earlier.
Key wordssnoRNA scaRNA sdRNA miRNA noncoding RNA RNA silencing oncogenesis
internal ribosome entry site
small Cajal body-specific RNAs
small nucleolar RNAs
small nuclear RNAs
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