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Biochemistry (Moscow)

, Volume 77, Issue 7, pp 707–715 | Cite as

Classification of phenoptotic phenomena

  • G. Libertini
Review

Abstract

Phenoptosis is defined as the programmed death of an organism. In a more detailed formulation of the concept, it is the death of an individual caused by its own actions or by actions of close relatives (and not by accidents or age-independent diseases), which is determined by genes that are favored by natural selection and in certain cases increase the evolvability of organisms. This category of phenomena cannot be justified in terms of individual selection and needs always a justification in terms of supra-individual selection. Four types of phenoptosis are proposed (A, obligatory and rapid; B, obligatory and slow; C, optional; D, indirect). Examples of each type and subtype are given. The classification is discussed in its meaning and implications, and compared with another classification of end life types largely based on the classical concept of senescence.

Key words

phenoptosis supra-individual selection senescence aging 

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References

  1. 1.
    Darwin, C. R. (1859) On the Origin of Species by Means of Natural Selection, or the Preservation 1 of the Favoured Races in the Struggle for Life, John Murray, London.Google Scholar
  2. 2.
    Hamilton, W. D. (1964) J. Theor. Biol., 7, 1–52.PubMedCrossRefGoogle Scholar
  3. 3.
    Hamilton, W. D. (1970) Nature, 228, 1218–1220.PubMedCrossRefGoogle Scholar
  4. 4.
    Trivers, R. L. (1971) Quart. Rev. Biol., 46, 35–57.CrossRefGoogle Scholar
  5. 5.
    Wilson, E. O. (1975) Sociobiology, The New Synthesis, Harvard University Press, Cambridge.Google Scholar
  6. 6.
    Nowak, A. M., Tarnita, C. E., and Wilson, E. O. (2010) Nature, 466, 1057–1062.PubMedCrossRefGoogle Scholar
  7. 7.
    Kirschner, M., and Gerhart, J. (1998) Proc. Natl. Acad. Sci. USA, 95, 8420–8427.PubMedCrossRefGoogle Scholar
  8. 8.
    Darwin, C. R. (1871) The Descent of Man, John Murray, London.Google Scholar
  9. 9.
    Skulachev, V. P. (2010) The Talk at the “From Homo sapiens to Homo sapiens liberatus” workshop, 2010, May 26, Moscow.Google Scholar
  10. 10.
    Schopenhauer, A. (1819) Die Welt als Wille und Vorstellung: Vier Bucher, nebst einem Anhange, der die Kritik der Kantischen Philosophie enthalt, Brockhaus, Leipzig (in English: The World as Will and Representation, Dover Publications, New York, 1969).Google Scholar
  11. 11.
    Skulachev, V. P. (1997) Biochemistry (Moscow), 62, 1191–1195.Google Scholar
  12. 12.
    Skulachev, V. P. (1999) Biochemistry (Moscow), 64, 1418–1426.Google Scholar
  13. 13.
    Finch, C. E. (1990) Longevity, Senescence, and the Genome, The University of Chicago Press, Chicago-London.Google Scholar
  14. 14.
    Kerr, J. F. R., Wyllie, A. H., and Currie, A. R. (1972) Br. J. Cancer, 26, 239–257.PubMedCrossRefGoogle Scholar
  15. 15.
    Hochman, A. (1997) Crit. Rev. Microbiol., 23, 207–214.PubMedCrossRefGoogle Scholar
  16. 16.
    Skulachev, V. P. (1999) Mol Aspects Med., 20, 139–184.PubMedCrossRefGoogle Scholar
  17. 17.
    Skulachev, V. P. (2003) in Topics in Current Genetics, Vol. 3 (Nystrom, T., and Osiewacz, H. D., eds.) Model Systems in Aging, Springer-Verlag, Berlin.Google Scholar
  18. 18.
    Skulachev, V. P. (2002) Ann. N. Y. Acad. Sci., 959, 214–237.PubMedCrossRefGoogle Scholar
  19. 19.
    Laun, P., Bruschi, C. V., Dickinson, J. R., Rinnerthaler, M., Heeren, G., Schwimbersky, R., Rid, R., and Breitenbach, M. (2007) Nucleic Acids Res., 35, 7514–7526.PubMedCrossRefGoogle Scholar
  20. 20.
    Buttner, S., Eisenberg, T., Herker, E., Carmona-Gutierrez, D., Kroemer, G., and Madeo, F. (2006) J. Cell Biol., 175, 521–525.PubMedCrossRefGoogle Scholar
  21. 21.
    Lewis, K. (2000) Microbiol. Mol. Biol. Rev., 64, 503–514.PubMedCrossRefGoogle Scholar
  22. 22.
    Jazwinski, S. M. (1993) Genetica, 91, 35–51.PubMedCrossRefGoogle Scholar
  23. 23.
    Libertini, G. (2006) The Scientific World J., 6, 1086–1108.CrossRefGoogle Scholar
  24. 24.
    Libertini, G. (2008) The Scientific World J., 8, 183–193.Google Scholar
  25. 25.
    Libertini, G. (1988) J. Theor. Biol., 132, 145–162.PubMedCrossRefGoogle Scholar
  26. 26.
    Holmes, D. J., and Austad, S. N. (1995) J. Gerontol. A Biol. Sci., 50, B59–66.CrossRefGoogle Scholar
  27. 27.
    Libertini, G. (2009) in Telomeres: Function, Shortening and Lengthening (Mancini, L., ed.) Nova Science Publishers Inc., New York.Google Scholar
  28. 28.
    Ricklefs, R. E. (1998) Am. Nat., 152, 24–44.PubMedCrossRefGoogle Scholar
  29. 29.
    Kirkwood, T. B. L., and Austad, S. N. (2000) Nature, 408, 233–238.PubMedCrossRefGoogle Scholar
  30. 30.
    Lane, N. (2008) Nature, 453, 583–585.PubMedCrossRefGoogle Scholar
  31. 31.
    Raff, M. C. (1998) Nature, 396, 119–122.PubMedCrossRefGoogle Scholar
  32. 32.
    Engelberg-Kulka, H., Sat, B., Reches, M., Amitai, S., and Hazan, R. (2004) Trends Microbiol., 12, 66–71.PubMedCrossRefGoogle Scholar
  33. 33.
    Koonin, E. V., and Aravind, L. (2002) Cell Death Differ., 9, 394–404.PubMedCrossRefGoogle Scholar
  34. 34.
    Fabrizio, P., and Longo, V. D. (2008) Biochim. Biophys. Acta, 1783, 1280–1285.PubMedCrossRefGoogle Scholar
  35. 35.
    Herker, E., Jungwirth, H., Lehmann, K. A., Maldener, C., Frohlich, K. U., Wissing, S., Buttner, S., Fehr, M., Sigrist, S., and Madeo, F. (2004) J. Cell Biol., 164, 501–507.PubMedCrossRefGoogle Scholar
  36. 36.
    Laun, P., Pichova, A., Madeo, F., Fuchs, J., Ellinger, A., Kohlwein, S., Dawes, I., Frohlich, K.-U., and Breitenbach, M. (2001) Mol. Microbiol., 39, 1166–1173.PubMedCrossRefGoogle Scholar
  37. 37.
    Granot, D., Levine, A., and Dor-Hefetz, E. (2003) FEMS Yeast Res., 4, 7–13.PubMedCrossRefGoogle Scholar
  38. 38.
    Madeo, F., Frohlich, E., Ligr, M., Grey, M., Sigrist, S. J., Wolf, D. H., and Frohlich, K. U. (1999) J. Cell Biol., 145, 757–767.PubMedCrossRefGoogle Scholar
  39. 39.
    Fabrizio, P., Battistella, L., Vardavas, R., Gattazzo, C., Liou, L. L., Diaspro, A., Dossen, J. W., Gralla, E. B., and Longo, V. D. (2004) J. Cell Biol., 166, 1055–1067.PubMedCrossRefGoogle Scholar
  40. 40.
    Longo, V. D., Mitteldorf, J., and Skulachev, V. P. (2005) Nat. Rev. Genet., 6, 866–872.PubMedCrossRefGoogle Scholar
  41. 41.
    Mitteldorf, J. (2006) Rejuvenation Res., 9, 346–350.PubMedCrossRefGoogle Scholar
  42. 42.
    Skulachev, V. P. (2002) FEBS Lett., 528, 23–26.PubMedCrossRefGoogle Scholar
  43. 43.
    Skulachev, V. P., and Longo, V. D. (2005) Ann. N. Y. Acad. Sci., 1057, 145–164.PubMedCrossRefGoogle Scholar
  44. 44.
    Altmann, S. A., and Altmann, J. (1970) Baboon Ecology: African Field Research, The University of Chicago Press, Chicago.Google Scholar
  45. 45.
    Hall, K. R. (1960) Behaviour, 16, 261–294.CrossRefGoogle Scholar
  46. 46.
    Armstrong, E. A. (1947) Bird Display and Behaviour: an Introduction to the Study of Bird Psychology, Lindsay Drummond, London (reprinted by Dover, New York, 1965).Google Scholar
  47. 47.
    Brown, R. G. (1962) Ibis, 104, 1–12.CrossRefGoogle Scholar
  48. 48.
    Gramza, A. F. (1967) Auk., 84, 72–86.Google Scholar
  49. 49.
    Bruce, H. M. (1959) Nature, 184, 105.PubMedCrossRefGoogle Scholar
  50. 50.
    Lechler, R., and Warrens, A. (2000) HLA in Health and Disease, Academic Press, San Diego, California.Google Scholar
  51. 51.
    Shiina, T., Inoko, H., and Kulski, J. K. (2004) Tissue Antigens, 64, 631–649.PubMedCrossRefGoogle Scholar
  52. 52.
    Slev, P. R., Nelson, A. C., and Potts, W. K. (2006) Curr. Opin. Immunol., 18, 608–616.PubMedCrossRefGoogle Scholar
  53. 53.
    Wedekind, C., Seebeck, T., Bettens, F., and Paepke, A. J. (1995) Proc. Biol. Sci., 260, 245–249.PubMedCrossRefGoogle Scholar
  54. 54.
    Wedekind, C., and Furi, S. (1997) Proc. Biol. Sci., 264, 1471–1479.PubMedCrossRefGoogle Scholar
  55. 55.
    Ober, C., Weitkamp, L. R., Cox, N., Dytch, H., Kostyu, D., and Elias, S. (1997) Am. J. Hum. Genet., 61, 497–504.PubMedCrossRefGoogle Scholar
  56. 56.
    Ober, C., Weitkamp, L., and Cox, N. (1999) in Advances in Chemical Signals in Vertebrates (Johnston, R. E., Muller-Schwarze, D., and Sorenson, P. W., eds.) Kluwer Academic Press, New York.Google Scholar
  57. 57.
    Loisel, D. A., Alberts, S. C., and Ober, C. (2008) in Evolution in Health and Disease (2nd Edn.) (Stearns, S. C., and Koella, J. C., eds.) Oxford University Press, Oxford.Google Scholar
  58. 58.
    Apanius, V., Penn, D., Slev, P. R., Ruff, L. R., and Potts, W. K. (1997) Crit. Rev. Immunol., 17, 179–224.PubMedCrossRefGoogle Scholar
  59. 59.
    Tregenza, T., and Wedell, N. (2000) Mol. Ecol., 9, 1013–1027.PubMedCrossRefGoogle Scholar
  60. 60.
    Dorak, M. T., Lawson, T., Machulla, H. K., Mills, K. I., and Burnett, A. K. (2002) Genes Immun., 3, 263–269.PubMedCrossRefGoogle Scholar
  61. 61.
    Ober, C., and van der Ven, K. (1997) in Current Topics in Microbiology and Immunology (Olding, L. B., ed.) Springer-Verlag, Berlin.Google Scholar
  62. 62.
    Ober, C. (1992) Exp. Clin. Immunogenet., 9, 1–14.PubMedGoogle Scholar
  63. 63.
    Ober, C., Hyslop, T., Elias, S., Weitkamp, L. R., and Hauck, W. W. (1998) Hum. Reprod., 13, 33–38.PubMedCrossRefGoogle Scholar
  64. 64.
    Hausfater, G., and Hrdy, S. B. (1984) Infanticide: Comparative and Evolutionary Perspectives, Aldine, New York.Google Scholar
  65. 65.
    Landy, H. J., and Keith, L. G. (1998) Hum. Reprod. Update, 4, 177–183.PubMedCrossRefGoogle Scholar
  66. 66.
    Scrimshaw, S. C. M. (1984) in Infanticide: Comparative and Evolutionary Perspectives (Hausfater, G., and Hrdy, S. B., eds.) Aldine, New York.Google Scholar
  67. 67.
    Eaton, S. B., Shostak, M., and Konner, M. (1988) The Paleolithic Prescription: a Program of Diet and Exercise and a Design for Living, Harper & Row, New York.Google Scholar
  68. 68.
    George, J., Bada, J., Zeh, J., Scott, L., Brown, S., O’Hara, T., and Suydam, R. (1999) Can. J. Zool., 77, 571–580.Google Scholar
  69. 69.
    Vaupel, J. W., Baudisch, A., Dolling, M., Roach, D. A., and Gampe, J. (2004) Theor. Popul. Biol., 65, 339–351.PubMedCrossRefGoogle Scholar

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© Pleiades Publishing, Ltd. 2012

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  • G. Libertini

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