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Biochemistry (Moscow)

, Volume 73, Issue 7, pp 742–750 | Cite as

Changes in regulation of cell—cell adhesion during tumor transformation

  • N. A. GloushankovaEmail author
Review

Abstract

Cadherin-mediated cell—cell adhesion defines the integrity of most tissues. Cell—cell adherens junctions are dynamic structures whose functional state is regulated by interactions of cadherin with β-catenin, p120, and actin cytoskeleton structures. Small GTPases of the Rho family and GTPase Rap1 play the central role in the formation and maintenance of cell—cell adhesion. Aberrant activation of signaling pathways, transcriptional repression of the E-cadherin gene, ectopic expression of N-cadherin, and disturbances in regulation of adhesive and transcriptional functions of β-catenin stimulate tumor progression.

Key words

cell—cell adherens junctions cadherins actin cytoskeleton epithelial-mesenchymal transformation 

Abbreviations

AJ

cell—cell adherens junctions

EGF

epidermal growth factor

EMT

epithelial-mesenchymal transformation

FGF

fibroblast growth factor

GEFs

guanine nucleotide exchange factors

HGF/SF

hepatocyte growth factor/scatter factor

PDGF

platelet-derived growth factor

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References

  1. 1.
    Willert, K., and Jones, K. A. (2007) Genes Dev., 20, 1394–1404.CrossRefGoogle Scholar
  2. 2.
    Perez-Moreno, M., and Fuchs, E. (2006) Dev. Cell, 11, 601–612.PubMedCrossRefGoogle Scholar
  3. 3.
    Katoh, M., and Katoh, M. (2006) Cancer Biol. Ther., 5, 1059–1064.PubMedGoogle Scholar
  4. 4.
    Erez, N., Bershadsky, A., and Geiger, B. (2005) Eur. J. Cell. Biol., 84, 235–244.PubMedCrossRefGoogle Scholar
  5. 5.
    Polakis, P. (2007) Curr. Opin. Genet. Dev., 17, 45–51.PubMedCrossRefGoogle Scholar
  6. 6.
    Takeichi, M. (1995) Curr. Opin. Cell. Biol., 7, 619–627.PubMedCrossRefGoogle Scholar
  7. 7.
    Gumbiner, B. M. (2000) J. Cell Biol., 148, 399–404.PubMedCrossRefGoogle Scholar
  8. 8.
    Gooding, J. M., Yap, K. L., and Ikura, M. (2004) BioEssays, 26, 497–511.PubMedCrossRefGoogle Scholar
  9. 9.
    Troyanovsky, S. (2005) Eur. J. Cell. Biol., 84, 225–233.PubMedCrossRefGoogle Scholar
  10. 10.
    Nagafuchi, A. (2001) Curr. Opin. Cell. Biol., 13, 600–603.PubMedCrossRefGoogle Scholar
  11. 11.
    Shapiro, L., Fannon, A. M., Kwong, P. D., Thompson, A., Lehmann, M. S., Grubel, G., Legrand, J. F., Als-Nielsen, J., Colman, D. R., and Hendrickson, W. A. (1995) Nature, 374, 327–337.PubMedCrossRefGoogle Scholar
  12. 12.
    Kobielak, A., and Fuchs, E. (2004) Nat. Rev. Mol. Cell. Biol., 5, 614–625.PubMedCrossRefGoogle Scholar
  13. 13.
    Kemler, R. (1993) Trends Genet., 9, 317–321.PubMedCrossRefGoogle Scholar
  14. 14.
    Rimm, D. L., Koslov, E. R., Kebriaei, P., Cianci, C. D., and Morrow, J. S. (1995) Proc. Natl. Acad. Sci. USA, 92, 8813–8817.PubMedCrossRefGoogle Scholar
  15. 15.
    Drees, F., Pokutta, S., Yamada, S., Nelson, W. J., and Weis, W. I. (2005) Cell, 123, 903–915.PubMedCrossRefGoogle Scholar
  16. 16.
    Yamada, S., Pokutta, S., Drees, F., Weis, W. I., and Nelson, W. J. (2005) Cell, 123, 889–901.PubMedCrossRefGoogle Scholar
  17. 17.
    Chu, Y. S., Thomas, W. A., Eder, O., Pincet, F., Perez, E., Thiery, J. P., and Dufour, S. (2004) J. Cell Biol., 167, 1183–1194.PubMedCrossRefGoogle Scholar
  18. 18.
    Sakisaka, T., Ikeda, W., Ogita, H., Fujita, N., and Takai, Y. (2007) Curr. Opin. Cell. Biol., 19, 593–602.PubMedCrossRefGoogle Scholar
  19. 19.
    Gloushankova, N. A., Alieva, N. O., Krendel, M. F., Bonder, E. M., Feder, H. H., Vasiliev, J. M., and Gelfand, I. M. (1997) Proc. Natl. Acad. Sci. USA, 94, 879–883.PubMedCrossRefGoogle Scholar
  20. 20.
    Krendel, M. F., and Bonder, E. M. (1999) Cell Motil. Cytoskeleton, 43, 296–309.PubMedCrossRefGoogle Scholar
  21. 21.
    Yonemura, S., Itoh, M., Nagafuchi, A., and Tsukita, S. (1995) J. Cell Sci., 108, 127–142.PubMedGoogle Scholar
  22. 22.
    Gloushankova, N. A., Krendel, M. F., Alieva, N. O., Bonder, E. M., Feder, H. H., Vasiliev, J. M., and Gelfand, I. M. (1998) Proc. Natl. Acad. Sci. USA, 95, 4362–4367.PubMedCrossRefGoogle Scholar
  23. 23.
    Krendel, M. F., Gloushankova, N. A., Alieva, N. O., Bonder, E. M., Feder, H. H., Vasiliev, J. M., and Gelfand, I. M. (1999) Proc. Natl. Acad. Sci. USA, 96, 9666–9670.PubMedCrossRefGoogle Scholar
  24. 24.
    Vasioukhin, V., Bauer, C., Yin, M., and Fuchs, E. (2000) Cell, 100, 209–219.PubMedCrossRefGoogle Scholar
  25. 25.
    Helwani, F. M., Kovacs, E. M., Paterson, A. D., Verma, S., Ali, R. G., Fanning, A. S., Weed, S. A., and Yap, A. S. (2004) J. Cell Biol., 164, 899–910.PubMedCrossRefGoogle Scholar
  26. 26.
    Verma, S., Shewan, A. M., Scott, J. A., Helwani, F. M., den Elzen, N. R., Miki, H., Takenawa, T., and Yap, A. S. (2004) J. Biol. Chem., 279, 34062–34070.PubMedCrossRefGoogle Scholar
  27. 27.
    Ivanov, A. I., Hunt, D., Utech, M., Nusrat, A., and Parkos, C. A. (2005) Mol. Biol. Cell, 16, 2636–2650.PubMedCrossRefGoogle Scholar
  28. 28.
    Higgs, H. N., and Pollard, T. D. (2001) Annu. Rev. Biochem., 70, 649–676.PubMedCrossRefGoogle Scholar
  29. 29.
    Kovacs, E. M., Goodwin, M., Ali, R. G., Paterson, A. D., and Yap, A. S. (2002) Curr. Biol., 12, 379–382.PubMedCrossRefGoogle Scholar
  30. 30.
    El Sayegh, T. Y., Arora, P. D., Laschinger, C. A., Lee, W., Morrison, C., Overall, C. M., Kapus, A., and McCulloch, C. A. (2004) J. Cell Sci., 117, 5117–5131.PubMedCrossRefGoogle Scholar
  31. 31.
    Yamazaki, D., Oikawa, T., and Takenawa, T. (2007) J. Cell. Sci., 120, 86–100.PubMedCrossRefGoogle Scholar
  32. 32.
    Goode, B. L., and Eck, M. J. (2007) Annu. Rev. Biochem., 76, 593–627.PubMedCrossRefGoogle Scholar
  33. 33.
    Kobielak, A., Pasolli, H. A., and Fuchs, E. (2004) Nat. Cell. Biol., 6, 21–30.PubMedCrossRefGoogle Scholar
  34. 34.
    Carramusa, L., Ballestrem, C., Zilberman, Y., and Bershadsky, A. D. (2007) J. Cell Sci., 120, 3870–3882.PubMedCrossRefGoogle Scholar
  35. 35.
    Zigmond, S. H. (2004) Curr. Opin. Cell Biol., 16, 99–105.PubMedCrossRefGoogle Scholar
  36. 36.
    Xu, Y., Moseley, J. B., Sagot, I., Poy, F., Pellman, D., Goode, B. L., and Eck, M. J. (2004) Cell, 116, 711–723.PubMedCrossRefGoogle Scholar
  37. 37.
    Higashida, C., Miyoshi, T., Fujita, A., Oceguera-Yanez, F., Monypenny, J., Andou, Y., Narumiya, S., and Watanabe, N. (2004) Science, 303, 2007–2010.PubMedCrossRefGoogle Scholar
  38. 38.
    Takaishi, K., Sasaki, T., Kotani, H., Nishioka, H., and Takai, Y. (1997) J. Cell Biol., 139, 1047–1059.PubMedCrossRefGoogle Scholar
  39. 39.
    Braga, V. M. M., Machesky, L. M., Hall, A., and Hotchin, N. A. (1997) J. Cell Biol., 137, 1421–1431.PubMedCrossRefGoogle Scholar
  40. 40.
    Kim, S. H., Li, Z., and Sacks, D. B. (2000) J. Biol. Chem., 275, 36999–37005.PubMedCrossRefGoogle Scholar
  41. 41.
    Kovacs, E. M., Ali, R. G., McCormack, A. J., and Yap, A. S. (2002) J. Biol. Chem., 277, 6708–6718.PubMedCrossRefGoogle Scholar
  42. 42.
    Ehrlich, J. S., Hansen, M. D., and Nelson, W. J. (2002) Dev. Cell, 3, 259–270.PubMedCrossRefGoogle Scholar
  43. 43.
    Fukata, M., and Kaibuchi, K. (2001) Nat. Rev. Mol. Cell. Biol., 2, 887–897.PubMedCrossRefGoogle Scholar
  44. 44.
    Welch, H. C., Coadwell, W. J., Stephens, L. R., and Hawkins, P. T. (2003) FEBS Lett., 546, 93–97.PubMedCrossRefGoogle Scholar
  45. 45.
    Stradal, T. E., Rottner, K., Disanza, A., Confalonieri, S., Innocenti, M., and Scita, G. (2004) Trends Cell Biol., 14, 303–311.PubMedCrossRefGoogle Scholar
  46. 46.
    Price, L. S., and Collard, J. G. (2001) Semin. Cancer Biol., 11, 167–173.PubMedCrossRefGoogle Scholar
  47. 47.
    Noritake, J., Watanabe, T., Sato, K., Wang, S., and Kaibuchi, K. (2005) J. Cell Sci., 118, 2085–2092.PubMedCrossRefGoogle Scholar
  48. 48.
    Kitayama, H., Sugimoto, Y., Matsuzaki, T., Ikawa, Y., and Noda, M. (1989) Cell, 56, 77–84.PubMedCrossRefGoogle Scholar
  49. 49.
    Yajnik, V., Paulding, C., Sordella, R., McClatchey, A. I., Saito, M., Wahrer, D. C., Reynolds, P., Bell, D. W., Lake, R., van den Heuvel, S., Settleman, J., and Haber, D. A. (2003) Cell, 112, 673–684.PubMedCrossRefGoogle Scholar
  50. 50.
    Kooistra, M. R., Dube, N., and Bos, J. L. (2007) J. Cell. Sci., 120, 17–22.PubMedCrossRefGoogle Scholar
  51. 51.
    Fukuyama, T., Ogita, H., Kawakatsu, T., Fukuhara, T., Yamada, T., Sato, T., Shimizu, K., Nakamura, T., Matsuda, M., and Takai, Y. (2005) J. Biol. Chem., 280, 815–825.PubMedGoogle Scholar
  52. 52.
    Kawajiri, A., Itoh, N., Fukata, M., Nakagawa, M., Yamaga, M., Iwamatsu, A., and Kaibuchi, K. (2000) Biochem. Biophys. Res. Commun., 273, 712–717.PubMedCrossRefGoogle Scholar
  53. 53.
    Hogan, C., Serpente, N., Cogram, P., Hosking, C. R., Bialucha, C. U., Feller, S. M., Braga, V. M., Birchmeier, W., and Fujita, Y. (2004) Mol. Cell. Biol., 24, 6690–6700.PubMedCrossRefGoogle Scholar
  54. 54.
    Fukuyama, T., Ogita, H., Kawakatsu, T., Inagaki, M., and Takai, Y. (2006) Oncogene, 25, 8–19.PubMedGoogle Scholar
  55. 55.
    Xiao, K., Oas, R. G., Chiasson, C. M., and Kowalczyk, A. P. (2007) Biochim. Biophys. Acta, 1773, 8–16.PubMedCrossRefGoogle Scholar
  56. 56.
    Retta, S. F., Balzac, F., and Avolio, M. (2006) Eur. J. Cell. Biol., 85, 283–293.PubMedCrossRefGoogle Scholar
  57. 57.
    Hirohashi, S. (1998) Am. J. Pathol., 153, 333–339.PubMedGoogle Scholar
  58. 58.
    Berx, G., and van Roy, F. (2001) Breast Cancer Res., 3, 289–293.PubMedCrossRefGoogle Scholar
  59. 59.
    Cavallaro, U., and Christofori, G. (2004) Nat. Rev. Cancer, 4, 118–132.PubMedGoogle Scholar
  60. 60.
    Hoschuetzky, H., Aberle, H., and Kemler, R. (1994) J. Cell. Biol., 127, 1375–1380.PubMedCrossRefGoogle Scholar
  61. 61.
    Boerner, J. L., Biscardi, J. S., Silva, C. M., and Parsons, S. J. (2005) Mol. Carcinog., 44, 262–273.PubMedCrossRefGoogle Scholar
  62. 62.
    Perrais, M., Chen, X., Perez-Moreno, M., and Gumbiner, B. M. (2007) Mol. Biol. Cell, 18, 2013–2025.PubMedCrossRefGoogle Scholar
  63. 63.
    Van Hengel, J., and van Roy, F. (2007) Biochim. Biophys. Acta, 1773, 78–88.PubMedCrossRefGoogle Scholar
  64. 64.
    Thiery, J. P. (2002) Nat. Rev. Cancer, 2, 442–454.PubMedCrossRefGoogle Scholar
  65. 65.
    Yoshiura, K., Kanai, Y., Ochiai, A., Shimoyama, Y., Sugimura, T., and Hirohashi, S. (1995) Proc. Natl. Acad. Sci. USA, 92, 7416–7419.PubMedCrossRefGoogle Scholar
  66. 66.
    Berx, G., Becker, K. F., Hofler, H., and van Roy, F. (1998) Hum. Mutat., 12, 226–237.PubMedCrossRefGoogle Scholar
  67. 67.
    Hajra, K. M., Ji, X., and Fearon, E. R. (1999) Oncogene, 18, 7274–7279.PubMedCrossRefGoogle Scholar
  68. 68.
    Di Croce, L., and Pelicci, P. G. (2003) Eur. J. Cancer, 39, 413–414.PubMedCrossRefGoogle Scholar
  69. 69.
    Peinado, H., Portillo, F., and Cano, A. (2004) Int. J. Dev. Biol., 48, 365–375.PubMedCrossRefGoogle Scholar
  70. 70.
    Koizume, S., Tachibana, K., Sekiya, T., Hirohashi, S., and Shiraishi, M. (2002) Nucleic Acids Res., 30, 4770–4780.PubMedCrossRefGoogle Scholar
  71. 71.
    Cano, A., Perez-Moreno, M. A., Rodrigo, I., Locasciop, A., Blanco, M. J., del Barrio, M. G., Portillo, F., and Nieto, M. A. (2000) Nat. Cell Biol., 2, 76–83.PubMedCrossRefGoogle Scholar
  72. 72.
    Comijn, J., Berx, G., Vermassen, P., Verschueren, K., van Grunsven, L., Bruyneel, E., Mareel, M., Huylebroeck, D., and van Roy, F. (2001) Mol. Cell, 7, 1267–1278.PubMedCrossRefGoogle Scholar
  73. 73.
    Bolos, V., Peinado, H., Perez-Moreno, M. A., Fraga, M. F., Esteller, M., and Cano, A. (2003) J. Cell Sci., 116, 499–511.PubMedCrossRefGoogle Scholar
  74. 74.
    Blanco, M. J., Moreno-Bueno, G., Sarrio, D., Locascio, A., Cano, A., Palacios, J., and Nieto, M. A. (2002) Oncogene, 21, 3241–3246.PubMedCrossRefGoogle Scholar
  75. 75.
    Jiao, W., Miyazaki, K., and Kitajima, Y. (2002) Br. J. Cancer, 86, 98–101.PubMedCrossRefGoogle Scholar
  76. 76.
    Batlle, E., Sancho, E., Franci, C., Dominguez, D., Monfar, M., Baulida, J., and Garcia de Herreros, A. (2000) Nat. Cell Biol., 2, 84–89.PubMedCrossRefGoogle Scholar
  77. 77.
    Barrallo-Gimeno, A., and Nieto, M. A. (2005) Development, 132, 3151–3161.PubMedCrossRefGoogle Scholar
  78. 78.
    Peinado, H., Olmeda, D., and Cano, A. (2007) Nat. Rev. Cancer, 7, 415–428.PubMedCrossRefGoogle Scholar
  79. 79.
    Larue, L., and Bellacosa, A. (2005) Oncogene, 24, 7443–7454.PubMedCrossRefGoogle Scholar
  80. 80.
    Alexander, N. R., Tran, N. L., Rekapally, H., Summers, C. E., Glackin, C., and Heimark, R. L. (2006) Cancer Res., 66, 3365–3369.PubMedCrossRefGoogle Scholar
  81. 81.
    De Craene, B., Gilbert, B., Stove, C., Bruyneel, E., van Roy, F., and Berx, G. (2005) Cancer Res., 65, 6237–6244.PubMedCrossRefGoogle Scholar
  82. 82.
    Reynolds, A. B. (2007) Biochim. Biophys. Acta, 1773, 2–7.PubMedCrossRefGoogle Scholar
  83. 83.
    Ireton, R. C., Davis, M. A., van Hengel, J., Mariner, D. J., Barnes, K., Thoreson, M. A., Anastasiadis, P. Z., Matrisian, L., Bundy, L. M., Sealy, L., Gilbert, B., van Roy, F., and Reynolds, A. B. (2002) J. Cell Biol., 159, 465–476.PubMedCrossRefGoogle Scholar
  84. 84.
    Hoshino, T., Sakisaka, T., Baba, T., Yamada, T., Kimura, T., and Takai, Y. (2005) J. Biol. Chem., 280, 42801–42808.PubMedCrossRefGoogle Scholar
  85. 85.
    Fujita, Y., Krause, G., Scheffner, M., Zechner, D., Leddy, H. E., Behrens, J., Sommer, T., and Birchmeier, W. (2002) Nat. Cell Biol., 4, 222–231.PubMedCrossRefGoogle Scholar
  86. 86.
    Dupre-Crochet, S., Figueroa, A., Hogan, C., Ferber, E. C., Bialucha, C. U., Adams, J., Richardson, E. C., and Fujita, Y. (2007) Mol. Cell. Biol., 27, 3804–3816.PubMedCrossRefGoogle Scholar
  87. 87.
    Kamei, T., Matozaki, T., Sakisaka, T., Kodama, A., Yokoyama, S., Peng, Y. F., Nakano, K., Takaishi, K., and Takai, Y. (1999) Oncogene, 18, 6776–6784.PubMedCrossRefGoogle Scholar
  88. 88.
    Xiao, K., Allison, D. F., Buckley, K. M., Kottke, M. D., Vincent, P. A., Faundez, V., and Kowalczyk, A. P. (2003) J. Cell Biol., 163, 535–545.PubMedCrossRefGoogle Scholar
  89. 89.
    Bryant, D. M., Wylie, F. G., and Stow, J. L. (2005) Mol. Biol. Cell, 16, 14–23.PubMedCrossRefGoogle Scholar
  90. 90.
    Kimura, T., Sakisaka, T., Baba, T., Yamada, T., and Takai, Y. (2006) J. Biol. Chem., 281, 10598–10609.PubMedCrossRefGoogle Scholar
  91. 91.
    Suzuki, K., and Takahashi, K. (2006) Biochem. Biophys. Res. Commun., 349, 255–260.PubMedCrossRefGoogle Scholar
  92. 92.
    Downing, J. R., and Reynolds, A. B. (1991) Oncogene, 6, 607–613.PubMedGoogle Scholar
  93. 93.
    Palacios, F., Tushir, J. S., Fujita, Y., and D’souza-Schorey, C. (2005) Mol. Cell. Biol., 25, 389–402.PubMedCrossRefGoogle Scholar
  94. 94.
    Mariner, D. J., Anastasiadis, P., Keilhack, H., Bohmer, F. D., Wang, J., and Reynolds, A. B. (2001) J. Biol. Chem., 276, 28006–28013.PubMedCrossRefGoogle Scholar
  95. 95.
    Yang, J. Y., Zong, C. S., Xia, W., Wei, Y., Ali-Seyed, M., Li, Z., Broglio, K., Berry, D. A., and Hung, M. C. (2006) Mol. Cell. Biol., 26, 7269–7282.PubMedCrossRefGoogle Scholar
  96. 96.
    Thoreson, M. A., and Reynolds, A. B. (2002) Differentiation, 70, 583–589.PubMedCrossRefGoogle Scholar
  97. 97.
    Chen, Y. T., Stewart, D. B., and Nelson, W. J. (1999) J. Cell Biol., 144, 687–699.PubMedCrossRefGoogle Scholar
  98. 98.
    Lilien, J., and Balsamo, J. (2005) Curr. Opin. Cell Biol., 17, 459–465.PubMedCrossRefGoogle Scholar
  99. 99.
    Roura, S., Miravet, S., Piedra, J., Garcia de Herreros, A., and Dunach, M. (1999) J. Biol. Chem., 274, 36734–36740.PubMedCrossRefGoogle Scholar
  100. 100.
    Piedra, J., Miravet, S., Castano, J., Palmer, H. G., Heisterkamp, N., Garcia de Herreros, A., and Dunach, M. (2003) Mol. Cell. Biol., 23, 2287–2297.PubMedCrossRefGoogle Scholar
  101. 101.
    Behrens, J., von Kries, J. P., Kuhl, M., Bruhn, L., Wedlich, D., Grosschedl, R., and Birchmeier, W. (1996) Nature, 382, 638–642.PubMedCrossRefGoogle Scholar
  102. 102.
    Huber, O., Korn, R., McLaughlin, J., Ohsugi, M., Herrmann, B. G., and Kemler, R. (1996) Mech. Dev., 59, 3–10.PubMedCrossRefGoogle Scholar
  103. 103.
    He, T. C., Sparks, A. B., Rago, C., Hermeking, H., Zawel, L., da Costa, L. T., Morin, P. J., Vogelstein, B., and Kinzler, K. W. (1998) Science, 281, 1509–1512.PubMedCrossRefGoogle Scholar
  104. 104.
    Shtutman, M., Zhurinsky, J., Simcha, I., Albanese, C., D’Amico, M., Pestell, R., and Ben-Ze’ev, A. (1999) Proc. Natl. Acad. Sci. USA, 96, 5522–5527.PubMedCrossRefGoogle Scholar
  105. 105.
    Tetsu, O., and McCormick, F. (1999) Nature, 398, 422–426.PubMedCrossRefGoogle Scholar
  106. 106.
    Shimokawa, T., Furukawa, Y., Sakai, M., Li, M., Miwa, N., Lin, Y. M., and Nakamura, Y. (2003) Cancer Res., 63, 6116–6120.PubMedGoogle Scholar
  107. 107.
    Gavert, N., and Ben-Ze’ev, A. (2007) J. Cell. Biochem., 102, 820–828.PubMedCrossRefGoogle Scholar
  108. 108.
    Brembeck, F. H., Rosario, M., and Birchmeier, W. (2006) Curr. Opin. Genet. Dev., 16, 51–59.PubMedCrossRefGoogle Scholar
  109. 109.
    Brembeck, F. H., Schwarz-Romond, T., Bakkers, J., Wilhelm, S., Hammerschmidt, M., and Birchmeier, W. (2004) Genes Dev., 18, 2225–2230.PubMedCrossRefGoogle Scholar
  110. 110.
    Behrens, J., Jerchow, B. A., Wurtele, M., Grimm, J., Asbrand, C., Wirtz, R., Kuhl, M., Wedlich, D., and Birchmeier, W. (1998) Science, 280, 596–599.PubMedCrossRefGoogle Scholar
  111. 111.
    Kishida, S., Yamamoto, H., Ikeda, S., Kishida, M., Sakamoto, I., Koyama, S., and Kikuchi, A. (1998) J. Biol. Chem., 273, 10823–10826.PubMedCrossRefGoogle Scholar
  112. 112.
    Liu, C., Li, Y., Semenov, M., Han, C., Baeg, G. H., Tan, Y., Zhang, Z., Lin, X., and He, X. (2002) Cell, 108, 837–847.PubMedCrossRefGoogle Scholar
  113. 113.
    Pinson, K. I., Brennan, J., Monkley, S., Avery, B. J., and Skarnes, W. C. (2000) Nature, 407, 535–538.PubMedCrossRefGoogle Scholar
  114. 114.
    Tolwinski, N. S., Wehrli, M., Rives, A., Erdeniz, N., DiNardo, S., and Wieschaus, E. (2003) Dev. Cell, 4, 407–418.PubMedCrossRefGoogle Scholar
  115. 115.
    Kramps, T., Peter, O., Brunner, E., Nellen, D., Froesch, B., Chatterjee, S., Murone, M., Zullig, S., and Basler, K. (2002) Cell, 109, 47–60.PubMedCrossRefGoogle Scholar
  116. 116.
    Townsley, F. M., Cliffe, A., and Bienz, M. (2004) Nat. Cell. Biol., 6, 626–633.PubMedCrossRefGoogle Scholar
  117. 117.
    Adachi, S., Jigami, T., Yasui, T., Nakano, T., Ohwada, S., Omori, Y., Sugano, S., Ohkawara, B., Shibuya, H., Nakamura, T., and Akiyama, T. (2004) Cancer Res., 64, 8496–8501.PubMedCrossRefGoogle Scholar
  118. 118.
    Herzig, M., Savarese, F., Novatchkova, M., Semb, H., and Christofori, G. (2007) Oncogene, 26, 2290–2298.PubMedCrossRefGoogle Scholar
  119. 119.
    Morin, P. J., Sparks, A. B., Korinek, V., Barker, N., Clevers, H., Vogelstein, B., and Kinzler, K. W. (1997) Science, 275, 1787–1790.PubMedCrossRefGoogle Scholar
  120. 120.
    De La Coste, A., Romagnolo, B., Billuart, P., Renard, C. A., Buendia, M. A., Soubrane, O., Fabre, M., Chelly, J., Beldjord, C., Kahn, A., and Perret, C. (1998) Proc. Natl. Acad. Sci. USA, 95, 8847–8851.CrossRefGoogle Scholar
  121. 121.
    Satoh, S., Daigo, Y., Furukawa, Y., Kato, T., Miwa, N., Nishiwaki, T., Kawasoe, T., Ishiguro, H., Fujita, M., Tokino, T., Sasaki, Y., Imaoka, S., Murata, M., Shimano, T., Yamaoka, Y., and Nakamura, Y. (2000) Nat. Genet., 24, 245–250.PubMedCrossRefGoogle Scholar
  122. 122.
    Groden, J., Thliveris, A., Samowitz, W., Carlson, M., Gelbert, L., Albertsen, H., Joslyn, G., Stevens, J., Spirio, L., and Robertson, M. (1991) Cell, 66, 589–600.PubMedCrossRefGoogle Scholar
  123. 123.
    Kawasaki, Y., Sato, R., and Akiyama, T. (2003) Nat. Cell. Biol., 5, 211–215.PubMedCrossRefGoogle Scholar
  124. 124.
    Zhou, B. P., Deng, J., Xia, W., Xu, J., Li, Y. M., Gunduz, M., and Hung, M. C. (2004) Nat. Cell Biol., 6, 931–940.PubMedCrossRefGoogle Scholar
  125. 125.
    Frame, S., and Cohen, P. (2001) Biochem. J., 359, 1–16.PubMedCrossRefGoogle Scholar
  126. 126.
    Ciruna, B., and Sleeman, J. (2006) Dev. Cell, 1, 37–49.CrossRefGoogle Scholar
  127. 127.
    Thiery, J. P., and Sleeman, J. (2006) Nat. Rev. Mol. Cell. Biol., 7, 131–142.PubMedCrossRefGoogle Scholar
  128. 128.
    Chamorro, M. N., Schwartz, D. R., Vonica, A., Brivanlou, A. H., Cho, K. R., and Varmus, H. E. (2005) EMBO J., 24, 73–84.PubMedCrossRefGoogle Scholar
  129. 129.
    Katoh, M., and Katoh, M. (2006) Int. J. Oncol., 29, 163–168.PubMedGoogle Scholar
  130. 130.
    El Sayegh, T. Y., Kapus, A., and McCulloch, C. A. (2007) FEBS Lett., 581, 167–174.PubMedCrossRefGoogle Scholar
  131. 131.
    El Sayegh, T. Y., Arora, P. D., Fan, L., Laschinger, C. A., Lee, W., Greer, P. A., Christopher, A., McCulloch, C. A., and Kapus, A. (2004) Mol. Biol. Cell, 16, 5514–5527.CrossRefGoogle Scholar
  132. 132.
    Derycke, L. D. M., and Bracke, M. E. (2004) Int. J. Dev., 48, 463–476.CrossRefGoogle Scholar
  133. 133.
    Nieman, M. T., Prudoff, R. S., Johnson, K. R., and Wheelock, M. J. (1999) J. Cell Biol., 147, 631–644.PubMedCrossRefGoogle Scholar
  134. 134.
    Hazan, R. B., Phillips, G. R., Qiao, R. F., Norton, L., and Aaronson, S. A. (2000) J. Cell Biol., 148, 779–790.PubMedCrossRefGoogle Scholar
  135. 135.
    Gaggioli, C., Hooper, S., Hidalgo-Carcedo, C., Grosse, R., Marshall, J. F., Harrington, K., and Sahai, E. (2007) Nat. Cell. Biol., 9, 1392–1400.PubMedCrossRefGoogle Scholar
  136. 136.
    Suyama, K., Shapiro, I., Guttman, M., and Hazan, R. B. (2002) Cancer Cell, 2, 301–314.PubMedCrossRefGoogle Scholar
  137. 137.
    Theisen, C. S., Wahl, J. K., III, Johnson, K. R., and Wheelock, M. J. (2007) Mol. Biol. Cell, 18, 1220–1232.PubMedCrossRefGoogle Scholar

Copyright information

© MAIK Nauka 2008

Authors and Affiliations

  1. 1.Blokhin Cancer Research CenterRussian Academy of Medical SciencesMoscowRussia

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