Biochemistry (Moscow)

, Volume 73, Issue 1, pp 1–13 | Cite as

Cysteine proteinases of microorganisms and viruses

  • G. N. RudenskayaEmail author
  • D. V. Pupov


This review considers properties of secreted cysteine proteinases of protozoa, bacteria, and viruses and presents information on the contemporary taxonomy of cysteine proteinases. Literature data on the structure and physicochemical and enzymatic properties of these enzymes are reviewed. High interest in cysteine proteinases is explained by the discovery of these enzymes mostly in pathogenic organisms. The role of the proteinases in pathogenesis of several severe diseases of human and animals is discussed.

Key words

cysteine proteinases properties protozoa bacteria viruses 





foot-and-mouth disease virus


RNA-dependent RNA polymerase


tosyl-L-lysine chloromethyl ketone


tosyl-L-phenylalanine chloromethyl ketone


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© Pleiades Publishing, Ltd. 2008

Authors and Affiliations

  1. 1.Faculty of ChemistryLomonosov Moscow State UniversityMoscowRussia
  2. 2.Faculty of BiologyLomonosov Moscow State UniversityMoscowRussia

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