Advertisement

Applied Biochemistry and Microbiology

, Volume 52, Issue 5, pp 471–475 | Cite as

Determination of residual protein and endotoxins in chitosan (review)

  • A. V. Il’ina
  • V. P. Varlamov
Article
  • 81 Downloads

Abstract

Methods for the determination of residual protein and endotoxins in chitosan preparations, which can be used as vectors for biologically active compounds delivery, are discussed. The limits of their use for the determination of residual impurities in chitosan preparations associated with the structure of the biopolymer are estimated.

Keywords

chitosan delivery vector residual protein endotoxins pyrogens 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Cheung, R.C.F., Ng, T.B., Wong, J.H., and Cha, W.Y., Mar. Drugs, 2015, vol. 13, no. 8, pp. 5156–5186.CrossRefPubMedPubMedCentralGoogle Scholar
  2. 2.
    Diaz-Rojas, E.I., Arguelles-Monal, W.M., Higuera-Ciapara, I., Hernandez, J., Lizardi-mendoza, J., and Goycoolea, F.M., Macromol. Biosci., 2006, vol. 6, no. 5, pp. 340–347.CrossRefPubMedGoogle Scholar
  3. 3.
    Fernandez-Pan, I., Mate, J.I., Gardrat, C., and Coma, V., Food Hydrocolloids, 2015, vol. 51, no. 1, pp. 60–68.CrossRefGoogle Scholar
  4. 4.
    Khitozan (Chitosan), Skryabin, K.G., Mikhailov, S.N., and Varlamov, V.P., Eds., Moscow Tsentr “Bioinzheneriya” RAN, 2013.Google Scholar
  5. 5.
    Ngo, D.H., Vo, T.S., Ngo, D.N., Kang, K.H., Je, J.Y., Pham, H.N.D., Byun, H.G., and Kim, S.K., Food Hydrocolloids, 2015, vol. 51, no. 1, pp. 200–216.CrossRefGoogle Scholar
  6. 6.
    Badwan, A.A., Rashid, I., Al Omari, M.H., and Darras, F.H., Mar. Drugs, 2015, vol. 13, no. 3, pp. 1519–1547.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    Kyzas, G.Z. and Bikiaris, D.N., Mar. Drugs, 2015, vol. 13, no. 1, pp. 312–337.CrossRefPubMedPubMedCentralGoogle Scholar
  8. 8.
    Younes, I. and Rinaudo, M., Mar. Drugs, 2015, vol. 13, no. 3, pp. 1133–1174.CrossRefPubMedPubMedCentralGoogle Scholar
  9. 9.
    Chien, R.C., Yen, M.T., and Mau, J.L., Carbohydr. Res., 2016, vol. 138, no. 1, pp. 259–264.CrossRefGoogle Scholar
  10. 10.
    Shagdarova, B.Ts., Il’ina, A.V., and Varlamov, V.P., Appl. Biochem. Microbiol., 2016, vol. 52, no. 2, pp. 222–225.CrossRefGoogle Scholar
  11. 11.
    Ghendon, Y., Markushin, S., Vasiliev, Y., Akopova, I., Koptiaeva, I., Krivtsov, G., Borisova, O., Ahmatova, N., Kurbatova, E., Mazurina, S., and Gervazieva, V., J. Med. Virol., 2009, vol. 81, no. 3, pp. 494–506.CrossRefPubMedGoogle Scholar
  12. 12.
    Szymanska, E. and Winnicka, K., Mar. Drugs, 2015, vol. 13, no. 4, pp. 1819–1846.CrossRefPubMedPubMedCentralGoogle Scholar
  13. 13.
    Alvarez, F.J., Molecules, 2014, vol. 19, no. 4, pp. 4433–4451.CrossRefPubMedGoogle Scholar
  14. 14.
    Dzung, N.A., Ha, N.T.N., Van, D.T.H., Phuong, N.T.L., Quynh, N.T.N., Hiep, D.M., and Hiep, L.V., World Acad. Sci. Eng. Technol., 2011, vol. 5, no. 1, pp. 12–22.Google Scholar
  15. 15.
    Aranaz, I., Mengibar, M., Harris, R., Panos, I., Miralles, B., Acosta, N., Galed, G., and Heras, A., Current Chem. Biol., 2009, vol. 3, no. 2, pp. 203–230.Google Scholar
  16. 16.
    Buske, S., Young, K., Weber, B., Rades, T., and Hook, S., Vaccine, 2013, vol. 31, no. 42, pp. 4812–4819.CrossRefPubMedGoogle Scholar
  17. 17.
    Li, B., Zhang, J., Dai, F., and Xia, W., Carbohydr. Res., 2012, vol. 88, no. 1, pp. 206–212.CrossRefGoogle Scholar
  18. 18.
    Gosudarstvennaya farmakopeya Rossiiskoi Federatsii (State Pharmacopoeia of the Russian Federation), Moscow: Nauchnyi tsentr ekspertizy sredstv meditsinskogo primeneniya, 2008, vol. XII, pt. 1.Google Scholar
  19. 19.
    Stoschech, C.M., Methods Enzymol., 1990, vol. 182, no. 1, pp. 50–68.CrossRefGoogle Scholar
  20. 20.
    Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J., J. Biol. Chem., 1951, vol. 193, no. 1, pp. 265–275.PubMedGoogle Scholar
  21. 21.
    Waffenschmidt, S. and Jaenicke, L., Anal. Biochem., 1987, vol. 165, no. 2, pp. 337–340.CrossRefPubMedGoogle Scholar
  22. 22.
    Bradford, M.M., Anal. Biochem., 1976, vol. 72, nos. 1–2, pp. 248–254.CrossRefPubMedGoogle Scholar
  23. 23.
    Chatterjee, S., Adhya, M., Guha, A.K., and Chatterjee, B.P., Proc. Biochem., 2004, vol. 40, no. 1, pp. 395–400.CrossRefGoogle Scholar
  24. 24.
    Gartman, O.R. and Vorob’eva, V.M., Fundam. Issled. Farmatsevt. Nauki, 2013, no. 6, pp. 1188–1192.Google Scholar
  25. 25.
    Loginova, O.O., Kholyavka, M.G., Artyukhov, V.G., and Belenova, A.S., Vestnik VGU, Ser. Khim. Biol. Farmats., 2013, no. 2, pp. 116–119.Google Scholar
  26. 26.
    Sandeep, A., Sangameshwar, K., Mukesh, G., Chandrakant, R., and Avinash, D., Indo Am. J. Pharm. Res., 2013, vol. 13, no. 12, pp. p. 1564–1574.Google Scholar
  27. 27.
    Gogichaeva, N.V., Williams, T., and Alterman, M.A., J. Am. Soc. Mass Spectrom., 2007, vol. 18, no. 2, pp. 279–284.CrossRefPubMedGoogle Scholar
  28. 28.
    Magalhães, P.O., Lopes, A.M., Mazzola, P.G., Rangel-Yagui, C., Penna, T.C.V., and Pessoa, A., J. Pharm. Pharmaceut. Sci., 2007, vol. 10, no. 3, pp. 388–404.Google Scholar
  29. 29.
    Morita, T., Tanaka, S., Nakamura, T., and Iwanaga, S., FEBS Lett., 1981, vol. 129, no. 2, pp. 318–321.CrossRefGoogle Scholar
  30. 30.
    Mikami, T., Nagasa, T., Matsumoto, T., Suzuki, S., and Suzuki, M., Microbiol. Immunol., 1982, vol. 26, no. 5, pp. 403–409.CrossRefPubMedGoogle Scholar
  31. 31.
    Nolte, A., Hossfeld, S., Post, M., Niederlaender, J., Walker, T., Schlensak, C., and Wendel, H.P., J. Mater. Sci.: Mater. Med., 2014, vol. 25, no. 5, pp. 2121–2130.Google Scholar
  32. 32.
    Hemker, H.C., Dieri, R.A., De Smedt, E., and Beguin, S., Thromb. Haemost., 2006, vol. 96, no. 5, pp. 553–561.PubMedGoogle Scholar
  33. 33.
    Daneshian, M., Guenther, A., Wendel, A., Hartung, T., and von Aulock, S., J. Immunol. Methods, 2006, vol. 313, nos. 1–2, pp. 169–175.CrossRefPubMedGoogle Scholar
  34. 34.
    Mazzotti, F., Beuttler, J., Zeller, R., Fink, U., Schindler, S., Wendel, A., Hartung, T., and von Aulock, S., J. Biomed. Mater. Res. A, 2007, vol. 80, no. 2, pp. 276–282.CrossRefPubMedGoogle Scholar

Copyright information

© Pleiades Publishing, Inc. 2016

Authors and Affiliations

  1. 1.Institute of Bioengineering, Fundamentals of Biotechnology Federal Research CenterRussian Academy of SciencesMoscowRussia

Personalised recommendations