Applied Biochemistry and Microbiology

, Volume 43, Issue 2, pp 115–138

2-C-methylerythritol phosphate pathway of isoprenoid biosynthesis as a target in identifying new antibiotics, herbicides, and immunomodulators: A review

  • Yu. V. Ershov

DOI: 10.1134/S0003683807020019

Cite this article as:
Ershov, Y.V. Appl Biochem Microbiol (2007) 43: 115. doi:10.1134/S0003683807020019


Specific inhibitors of 2-C-methylerythritol phosphate pathway (MEP-pathway), including compounds obtained based on its metabolites, may compose a new class of antibiotics combining high efficiency and low toxicity. MEP-pathway of isoprenoid biosynthesis is a promising target in identifying new herbicides, immunomodulators, and other physiologically active compounds.

Copyright information

© Pleiades Publishing, Inc. 2007

Authors and Affiliations

  • Yu. V. Ershov
    • 1
  1. 1.Bach Institute of BiochemistryRussian Academy of SciencesMoscowRussia

Personalised recommendations