Journal of Experimental and Theoretical Physics

, Volume 91, Issue 4, pp 832–843 | Cite as

Interaction of nucleic acid segments as a result of modification of the network of hydrogen bonds of the solvent

  • V. L. Golo
  • Yu. M. Yevdokimov
  • E. I. Kats
  • V. I. Salyanov


It is shown that experimental results on the influence of various factors in the formation efficiency and structure of cholesteric liquid-crystal dispersions of nucleic acids cannot be consistently described using conventional theories of liquid crystal formation. A new model is proposed for the interaction of nucleic acid segments which allows for a change in the particular structure of the solvent hydrogen bonds in the presence of nucleic acid molecules. The conclusions of the model agree with existing spectroscopic and structural investigations of DNA dispersions. According to our model, interaction between nucleic acid molecules and solvent modifies proton tunneling processes in the latter, leading to effective interaction between the nucleic acids. A theoretical analysis of the model is made using a pseudospin formalism in which the effective interaction potential of the nucleic acid segments is calculated. It is shown that this potential may lead to nematic ordering for small distances between the nucleic acid molecules (R ≤ 30 Å) and cholesteric ordering for large distances.


Hydrogen Bond Nucleic Acid Elementary Particle Liquid Crystal Crystal Formation 
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Copyright information

© MAIK "Nauka/Interperiodica" 2000

Authors and Affiliations

  • V. L. Golo
    • 1
  • Yu. M. Yevdokimov
    • 2
  • E. I. Kats
    • 3
    • 4
  • V. I. Salyanov
    • 2
  1. 1.Moscow State UniversityMoscowRussia
  2. 2.Engelhardt Institute of Molecular BiologyRussian Academy of SciencesMoscowRussia
  3. 3.Landau Institute for Theoretical PhysicsRussian Academy of SciencesMoscowRussia
  4. 4.Laue-Langevin InstituteGrenobleFrance

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