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The Effect of Pulsed Ultrasound on Mandibular Distraction

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Abstract

This study evaluated the effect of pulsed ultrasound on tissue repair and bone growth during mandibular osteodistraction. Twenty-one rabbits were divided into three groups of 7. The distraction started 72 h after surgically severing both sides of the mandible and proceeded at a rate of 1.5 mm/12 h for 5 days. Group 1 received pulsed ultrasound (nominally 200 μs pulse of 1.5 MHz at a 1.1 kHz pulse repetition frequency, 30 mW/cm2) for 20 min on both sides of the mandible every other day (alternating sides). Group 2 received the same pulsed ultrasound treatment on one side of the mandible every day for 20 min. Group 3 did not receive any ultrasound treatment. Bone formation at the distraction site was assessed by photodensitometry on head radiographs, a vibratory coherence test across the distraction site, a postmortem three-point bending mechanical stiffness test, and a postmortem histological examination. Statistical analyses performed using analysis of variance revealed that pulsed ultrasound enhanced bone formation at the distraction site with a high level of significance when assessed by the increase in new bone photodensity (p=0.001), vibratory coherence (p=0.001), mechanical stiffness (p=0.003), and qualitative histological studies, especially when the pulsed ultrasound treatment was directly applied daily. © 2002 Biomedical Engineering Society.

PAC2002: 8750Kk, 8763Df

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Authors and Affiliations

  1. Tanta University, Egypt and Department of Bioengineering, University of Illinois at Chicago, 851 South Morgan Street, M/C 063, Room 212, Chicago, IL

    Tarek H. El-Bialy

  2. Department of Mechanical Engineering, University of Illinois at Chicago, 2039 Engineering Research Facility, 842 West Taylor Street, Chicago, IL

    Thomas J. Royston

  3. Department of Bioengineering, University of Illinois at Chicago, 851 South Morgan Street, Room 218, Chicago, IL

    Richard L. Magin

  4. Department of Orthodontics, University of Illinois at Chicago, 801 South Paulina Street, Chicago, IL

    Carla A. Evans

  5. University of Illinois at Chicago, 801 South Paulina Street, Room 431, Chicago, IL

    Abd El-Moneim Zaki

  6. Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, 405 North Mathews Avenue, Urbana, IL

    Leon A. Frizzell

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  1. Tarek H. El-Bialy
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  3. Richard L. Magin
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El-Bialy, T.H., Royston, T.J., Magin, R.L. et al. The Effect of Pulsed Ultrasound on Mandibular Distraction. Annals of Biomedical Engineering 30, 1251–1261 (2002). https://doi.org/10.1114/1.1529196

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