Annals of Biomedical Engineering

, Volume 27, Issue 6, pp 763–773

Vortex Shedding in Steady Flow Through a Model of an Arterial Stenosis and Its Relevance to Mural Platelet Deposition

  • Danny Bluestein
  • Carlos Gutierrez
  • Mateo Londono
  • Richard T. Schoephoerster


In this study, the development of unsteady vortical formations in the separated flow region distal to a stenosis throat is presented and compared with the platelet deposition measurements, to enhance our understanding of the mechanisms involved in platelet kinetics in flowing blood. Qualitative and quantitative flow visualization and numerical simulations were performed in a model of a streamlined axisymmetric stenosis with an area reduction of 84% at the throat of the stenosis. Measurements were performed at Reynolds numbers (Re), based on upstream diameter and average velocity, ranging from 300 to 1800. Both the digital particle image visualization method employed and the numerical simulations were able to capture the motion of the vortices through the separated flow region. Periodic shedding of vortices began at approximately Re=375 and continued for the full range of Re studied. The locales at which these vortices are initiated, their size, and their life span, were a function of Re. The numerical simulations of turbulent flow through the stenosis model entailed a detailed depiction of the process of vortex shedding in the separated flow region downstream of the stenosis. These flow patterns were used to elucidate the mechanisms involved in blood platelet kinetics and deposition in the area in and around an arterial stenosis. The unsteady flow development in the recirculation region is hypothesized as the mechanism for observed changes in the distribution of mural platelet deposition between Re=300, 900, and 1800, despite only a marginal variation in the size and shape of the recirculation zone under these flow conditions. © 1999 Biomedical Engineering Society.

PAC99: 8719Uv, 8710+e

Blood flow Cardiovascular pathologies Platelet activation and aggregation CFD DPIV 


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Copyright information

© Biomedical Engineering Society 1999

Authors and Affiliations

  • Danny Bluestein
    • 1
  • Carlos Gutierrez
    • 2
  • Mateo Londono
    • 2
  • Richard T. Schoephoerster
    • 2
  1. 1.Program in Biomedical EngineeringState University of New York at Stony BrookStony Brook
  2. 2.Mechanical Engineering DepartmentFlorida International UniversityMiami

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