Annals of Biomedical Engineering

, Volume 29, Issue 3, pp 252–262 | Cite as

Lung Area–Volume Models in Relation to the Recruitment–Derecruitment of Individual Lung Units

  • L. Brancazio
  • G. N. Franz
  • E. L. Petsonk
  • D. G. Frazer


The objective of this study was to reconsider some of the previous experimental results in terms of simple geometric models in order to determine if any of the apparent conflicts could be explained within a more unified concept. These models allow individual lung units and the entire lung to expand differently with regard to their area–volume relationship. The effect of a recruitment–derecruitment process as the lung inflates–deflates is also considered. Examples are used to illustrate how some of the apparent conflicts found in the literature may arise from whether or not recruitment and derecruitment take place during lung expansion and contraction. © 2001 Biomedical Engineering Society.

PAC01: 8719Uv, 8710+e

Geometric irreversibility of the lung Lung area–volume models Lung units Lung expansion Lung mechanics 


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Copyright information

© Biomedical Engineering Society 2001

Authors and Affiliations

  • L. Brancazio
    • 1
  • G. N. Franz
    • 2
  • E. L. Petsonk
    • 3
  • D. G. Frazer
    • 4
    • 2
  1. 1.Department of Obstetrics and GynecologyWest Virginia University School of MedicineMorgantown
  2. 2.Department of PhysiologyWest Virginia University School of MedicineMorgantown
  3. 3.Division of Respiratory DiseasesNational Institute for Occupational Safety and HealthMorgantown
  4. 4.Health Effects Laboratory DivisionNational Institute for Occupational Safety and HealthMorgantown

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