Sleep and Biological Rhythms

, Volume 11, Supplement 1, pp 21–26 | Cite as

Cognitive dysfunction in rapid eye movement sleep behavior disorder

  • Josie-Anne Bertrand
  • Daphné Génier Marchand
  • Ronald B. Postuma
  • Jean-François Gagnon
Review Article


Cognitive impairment is a frequent feature of rapid eye movement sleep behavior disorder (RBD). The cognitive profile of RBD patients is heterogeneous, with impairments in attention, executive functions, episodic memory, and visuospatial abilities. Moreover, over 50% of RBD patients meet the diagnostic criteria for mild cognitive impairment (MCI). Although a comprehensive neuropsychological assessment remains the most sensitive way to detect MCI, three cognitive screening tests have been validated in RBD. The Montreal Cognitive Assessment was found to be the most appropriate screening test for detecting MCI in RBD. In addition RBD in Parkinson’s disease may be a risk factor for MCI and dementia.

Key words

dementia with Lewy bodies mild cognitive impairment Parkinson’s disease REM sleep behavior disorder 


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Copyright information

© Japanese Society of Sleep Research 2012

Authors and Affiliations

  • Josie-Anne Bertrand
    • 1
    • 2
  • Daphné Génier Marchand
    • 1
    • 3
  • Ronald B. Postuma
    • 1
    • 4
  • Jean-François Gagnon
    • 1
    • 3
  1. 1.Centre d’Études Avancées en Médecine du SommeilHôpital du Sacré-Cœur de MontréalMontréalCanada
  2. 2.Department of PsychologyUniversité de MontréalMontrealCanada
  3. 3.Department of PsychologyUniversité du Québec à MontréalMontrealCanada
  4. 4.Department of NeurologyMontreal General HospitalMontrealCanada

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