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Sleep and Biological Rhythms

, Volume 4, Issue 1, pp 75–77 | Cite as

Subjective effects of glycine ingestion before bedtime on sleep quality

  • Kentaro InagawaEmail author
  • Takenori Hiraoka
  • Tohru Kohda
  • Wataru Yamadera
  • Michio Takahashi
Short Paper

Abstract

The effects of glycine on sleep quality were examined in a randomized double-blinded cross-over trial. The volunteers, with complaints about the quality of their sleep, ingested either glycine (3 g) or placebo before bedtime, and their subjective feeling in the following morning was evaluated with the St. Mary’s Hospital Sleep Questionnaire and Space-Aeromedicine Fatigue Checklist. The glycine ingestion significantly improved the following elements: “fatigue”, “liveliness and peppiness”, and “clear-headedness”. These results suggest that glycine produced a good subjective feeling after awakening from sleep.

Key words

amino acid glycine subjective effect on sleep 

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Copyright information

© Japanese Society of Sleep Research 2006

Authors and Affiliations

  • Kentaro Inagawa
    • 1
    Email author
  • Takenori Hiraoka
    • 2
  • Tohru Kohda
    • 2
  • Wataru Yamadera
    • 3
  • Michio Takahashi
    • 1
  1. 1.Research Institute for Health FundamentalsAjinomoto Co., Inc.Kasawaki-shiJapan
  2. 2.Health Service Development DepartmentAjinomoto Co., Inc.TokyoJapan
  3. 3.Department of PsychiatryJikei University School of MedicineTokyoJapan

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