Subjective effects of glycine ingestion before bedtime on sleep quality
- 17 Downloads
The effects of glycine on sleep quality were examined in a randomized double-blinded cross-over trial. The volunteers, with complaints about the quality of their sleep, ingested either glycine (3 g) or placebo before bedtime, and their subjective feeling in the following morning was evaluated with the St. Mary’s Hospital Sleep Questionnaire and Space-Aeromedicine Fatigue Checklist. The glycine ingestion significantly improved the following elements: “fatigue”, “liveliness and peppiness”, and “clear-headedness”. These results suggest that glycine produced a good subjective feeling after awakening from sleep.
Key wordsamino acid glycine subjective effect on sleep
Unable to display preview. Download preview PDF.
- 1.Cooper JR, Bloom FE, Roth RH. Amino acid transmitters. In: Cooper JR, Bloom FE and Roth RH, eds. The Biochemical Basis of Neuropharmacology, 8th edn. Oxford University Press: Oxford, 2003; 105–50.Google Scholar
- 4.Uchiyama M, Ohta K, Okawa M. Evaluation standards of sleep and sleep disorder. In: Matsushita M, ed. Encyclopedia of Clinical Psychiatry, Vol. 13, Sleep Disorder. Nakayama Shoten: Tokyo, 1999; 489–98 (in Japanese).Google Scholar
- 6.Yamadera W. Psychophysical and psychological consequences after surgical treatment of obstructive sleep apnea syndrome. Psychiatr. Neurol. Jap 1994; 96: 903–32 (in Japanese).Google Scholar
- 8.Doi Y, Minowa M, Uchiyama M, Okawa M. Development of the Pittsuburgh Sleep Quality Index Japanese version. Jap. J. Psychiatr. Treat. 1998; 13: 755–68 (in Japanese).Google Scholar