Fisheries Science

, 71:948

Kinetics of diarrhetic shellfish poisoning toxins, okadaic acid, dinophysistoxin-1, pectenotoxin-6 and yessotoxin in scallops Patinopecten yessoensis

  • Toshiyuki Suzuki
  • Tomoji Igarashi
  • Kazuhiko Ichimi
  • Masatoshi Watai
  • Megumi Suzuki
  • Eri Ogiso
  • Takeshi Yasumoto
Article

Abstract

Four toxins, okadaic acid (OA), dinophysistoxin-1 (DTX1), pectenotoxin-6 (PTX6), and yessotoxin (YTX), all associated with diarrhetic shellfish poisoning (DSP), were administered via syringe to Scallops Patinopecten yessoensis and their distribution in the hepatopancreas, adductor muscle, and combined other tissues (mantle, gill, gonad) was analyzed by liquid chromatography-mass spectrometry. Toxins exclusively remained in the hepatopancreas irrespective of the injection site, adductor muscle or hepatopancreas. When injected into hepatopancreas, OA, DTX1, and YTX were metabolized to 7-O-palmitoylOA, 7-O-palmitoylDTX1 and 45-hydroxyyessotoxin (45OH-YTX), respectively. Such metabolic changes were insignificant when toxins were injected into the adductor muscle. The residual ratio for each toxin in the hepatopancreas was less than 20%. Mortalities of scallops treated with PTX6 were lower than those treated with other toxins.

Key Words

dinophysistoxin-1 diarrhetic shellfish poisoning kinetics liquid chromatography-mass spectrometry okadaic acid pectenotoxin-6 scallops yessotoxin 

Copyright information

© The Japanese Society of Fisheries Science 2005

Authors and Affiliations

  • Toshiyuki Suzuki
    • 1
  • Tomoji Igarashi
    • 2
  • Kazuhiko Ichimi
    • 3
  • Masatoshi Watai
    • 2
  • Megumi Suzuki
    • 2
  • Eri Ogiso
    • 2
  • Takeshi Yasumoto
    • 2
  1. 1.Tohoku National Fisheries Research InstituteShiogama, MiyagiJapan
  2. 2.Japan Food Research LaboratoriesTokyoJapan
  3. 3.Marine Environment Research StationKagawa UniversityKita, KagawaJapan

Personalised recommendations