Skip to main content

Advertisement

Log in

A syringe prescription program to prevent infectious disease and improve health of injection drug users

  • Published:
Journal of Urban Health Aims and scope Submit manuscript

Abstract

Injection drug users (IDUs) are at increased risk for many health problems, including acquisition of human immunodeficiency virus (HIV) and hepatitis B and C. These risks are compounded by barriers in obtaining legal, sterile syringes and in accessing necessary medical care. In 1999, we established the first-ever syringe prescription program in Providence, Rhode Island, to provide legal access to sterile syringes, reduce HIV risk behaviors, and encourage entry into medical care. Physicians provided free medical care, counseling, disease testing, vaccination, community referrals, and prescriptions for sterile syringes for patients who were not ready to stop injecting. We recruited 327 actively injecting people. Enrolled participants had limited stable contact with the health care system at baseline; 45% were homeless, 59% were uninsured, and 63% did not have a primary care physician. Many reported high-risk injection behaviors such as sharing syringes (43% in the last 30 days), reusing syringes (median of eight times), and obtaining syringes from unreliable sources (80%). This program demonstrates the feasibility, acceptability, and unique features of syringe prescription for IDUs. The fact that drug use is acknowledged allows an open and frank discussion of risk behaviors and other issues often not disclosed to physicians. The syringe prescription program in Providence represents a promising and innovative approach to disease prevention and treatment for IDUs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Centers for Disease Control and Prevention. IDU/HIV prevention: access to sterile syringes. March 2001. Available at: www.cdc.gov/idu/facts/aed_idu_acc.html. Accessed December 1, 2002.

  2. Holmberg SD. The estimated prevalence and incidence of HIV in 96 large U.S. metropolitan areas. Am J Public Health, 1996;86:642–651.

    CAS  PubMed  Google Scholar 

  3. Centers for Disease Control and Prevention. Drug-associated HIV transmission continues in the United States. November 2000. Available at: www.cdc.gov/hiv/pubs/facts/idu.html. Accessed December 1, 2002.

  4. Garfein RS, Doherty MC, Monterroso ER, et al. Prevalence and incidence of hepatitis C virus infection among adult injection drug users. J Acquir Immune Defic Syndr Hum Retrovirol. 1998;18(suppl 1):S11-S19.

    PubMed  Google Scholar 

  5. Alter MJ, Moyer LA. The importance of preventing hepatitis C virus infection among injection drug users in the United States. J Acquir Immune Defic Syndr Hum Retrovirol. 1990;18(suppl 1):S6-S10.

    Google Scholar 

  6. Garfein RS, Valverde R, Swartzendruber A, et al. Differences in correlates of HIV, hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among young, street-recruited injection drug users (IDUs) in United States metropolitan areas. Paper presented at: 2002 International Conference on HIV/AIDS, Atlanta, GA.

  7. Friedland G, Selwyn P. Infections (excluding AIDS) in injection drug users. In: Fauci AS, Braunwald E, Isselbacher K, et al., eds. Harrison’s Principles of Internal Medicine. 14th ed. New York: McGraw-Hill; 1999:831–835.

    Google Scholar 

  8. Stein, MD. Medical consequences of substance abuse. Addict Disord. 1999;22:351–370.

    CAS  Google Scholar 

  9. Sporer KA. Acute heroin overdose. Ann Intern Med. 1999;130:584–590.

    CAS  PubMed  Google Scholar 

  10. Mylonakis E, Koutkia P, Rich JD, et al. Substance abuse is responsible for most pre-AIDS deaths among women with HIV infection in Providence, Rhode Island [letter]. AIDS. 1998;12:958–959.

    CAS  PubMed  Google Scholar 

  11. Gershon RR. Infection control basis for recommending one-time use of sterile syringes and aseptic procedures for injection drug users. J Acquir Immune Defic Syndr Hum Retrovirol. 1998;18(suppl 1):S20-S24.

    PubMed  Google Scholar 

  12. Spijkerman IJ, van Ameijden EJ, Mientjes GH, et al. Human immunodeficiency virus infection and other risk factors for skin abscesses and endocarditis among injection drug users. J Clin Epidemiol. 1996;49:1149–1154.

    Article  CAS  PubMed  Google Scholar 

  13. Stein MD, Friedmann PD. Need for medical and psychosocial services among injection drug users: a comparative study of needle exchange and methadone maintenance. Am J Addict. 2002;11:262–270.

    Article  PubMed  Google Scholar 

  14. Berthel T. Psychiatric and substance use comorbidity in medically controlled heroin prescription programs: prevalence rates, development of mental health state, treatment issues. In: Proceedings, the First International Conference on Heroin Maintenance; June 6, 1998; New York, NY.

  15. Pugatch D, Strong LL, Has P, et al. Heroin use in adolescents and young adults admitted for drug detoxification. J Subst Abuse. 2001;13:337–346.

    Article  CAS  PubMed  Google Scholar 

  16. McGarry KA, Stein MD, Clarke JG, Friedmann PD. Utilization of preventive health services by HIV-seronegative injection drug users. J Addict Stud. 2002;21:93–102.

    Article  Google Scholar 

  17. O’Connor PG, Selwyn PA, Schottenfeld RS. Medical care for injection drug users with human immunodeficiency virus infection. N Engl J Med. 1994;331:450–459.

    Article  CAS  PubMed  Google Scholar 

  18. Knowlton AR, Hoover DR, Chung SE, et al. Access to medical care and service utilization among injection drug users with HIV/AIDS. Drug Alcohol Depend. 2001;64:55–62.

    Article  CAS  PubMed  Google Scholar 

  19. Rich JD, Whitlock TL, Towe CW, et al. Prescribing syringes to prevent HIV: a survey of infectious disease and addiction medicine physicians in Rhode Island. Subst Use Misuse. 2001;36:535–550.

    Article  CAS  PubMed  Google Scholar 

  20. Bangsberg D, Tulsky JP, Hecht FM, et al. Protease inhibitors in the homeless. JAMA. 1997;278:63–65.

    Article  CAS  PubMed  Google Scholar 

  21. Celentano DD, Vlahov D, Cohn S, Shadle VM, Obasanjo O, Moore RD. Self-reported antiretroviral therapy in injection drug users. JAMA. 1998;280:544–546.

    Article  CAS  PubMed  Google Scholar 

  22. Strathdee S, Papepu A, Cornelisse P, et al. Antiretroviral therapy in injection drug users. JAMA. 1998;280:544–546.

    Article  Google Scholar 

  23. Gunn N, White C, Srinivasan R. Primary care as harm reduction for injection drugs users. Proc Assoc Am Phys. 1999;111:119–125.

    Article  Google Scholar 

  24. O’Connor P, Molde S, Henry S, Shockor W, Schottenfeld R. Human immunodeficiency virus infection in intravenous drug users: a model for primary care. Am J Med. 1992;93:382–386.

    Article  CAS  PubMed  Google Scholar 

  25. Centers for Disease Control and Prevention. Access to sterile syringes. January 2002. Available at: http://www.cdc.gov/idu/facts/aed_idu_acc.htm. Accessed October 20, 2003.

  26. Rich JD, Dickinson BP, Liu KL, et al. Strict syringe laws in Rhode Island are associated with high rates of reusing syringes and HIV risks among injection drug users. J Acquir Immune Defic Syndr Hum Retrovirol. 1998;18(uppl 1):S140-S141.

    PubMed  Google Scholar 

  27. Gostin LO, Lazzarini Z, Jones TS, et al. Prevention of HIV/AIDS and other blood-borne diseases among injection drug users: a national survey on the regulation of syringes and needles. JAMA. 1997;227:53–62.

    Article  Google Scholar 

  28. Broadhead RS, van Hulst Y, Heckathorn DD. The impact of a needle exchange’s closure. Public Health Rep. 1999;114:439–447.

    Article  CAS  PubMed  Google Scholar 

  29. Normand J, Vlahov D, Moses LE, eds. Preventing HIV Transmission: the Role of Sterile Needles and Bleach, Washington, DC: National Research Council/Institute of Medicine, National Academy Press; 1995.

    Google Scholar 

  30. US Department of Health and Human Services. HIV Prevention bulletin: medical advice for persons who inject illicit drugs. May 9, 1997. Available at: http://www.cdc.gov/idu/pubs/hiv_prev.htm. Accessed October 20, 2003.

  31. Rich JD, Strong L, Towe CW, McKenzie M. Obstacles to needle exchange participation in Rhode Island. J Acquir Immun Defic Syndr. 1999;21(5):396–400.

    CAS  Google Scholar 

  32. Rich JD, Strong LL, Mehrotra M, Macalino G. Strategies to optimize impact of needle exchange programs. AIDS Read. 2000;10:421–429.

    CAS  PubMed  Google Scholar 

  33. Des Jarlais DC. Research, politics, and needle exchange. Am J Public Health. 2000;90:1392–1394.

    Article  PubMed  Google Scholar 

  34. Groseclose SL, Weinstein B, Jones ST, et al. Impact of increased legal access to needles and syringes on practices of injecting-drug users and police officers—Connecticut, 1992–1993. J Acquir Immune Defic Syndr. 1995;10:82–89.

    CAS  Google Scholar 

  35. Novotny G, DeBoer J, Collison E, et al. Minnesota Department of Health. Minnesota pharmacy syringe/needle access initiative (SAI) implementation. Paper presented at: 1999 National HIV Prevention Conference; August 29–September 1, 1999; Atlanta, Abstract 141.

  36. Gostin LO. The legal environment impeding access to sterile syringes and needles: the conflict between law enforcement and public health. J Acquir Immune Defic Syndr. 1998;18(S1):S60-S70.

    Google Scholar 

  37. Burris S, Lurie P, Abrahamson D, et al. Physician prescribing of sterile injection equipment to prevent HIV infection: time for action. Ann Intern Med. 2000;133:218–226.

    CAS  PubMed  Google Scholar 

  38. Rich JD, Macalino G, McKenzie M, et al. Syringe prescription to prevent HIV infection in Rhode Island: a case study. Am J Public Health. 2001;91:699–700.

    CAS  PubMed  Google Scholar 

  39. AIDS associated with injection drug use, United States, 1995. MMWR Morb Mortal Wkly Rep. 1996;45:392–398.

    Google Scholar 

  40. Rich JD, Martin EG, Macalino GE, et al. Pharmacist support for selling syringes without a prescription to injection drug users in Rhode Island. J Am Pharm Assoc (Wash). 2002;42(6 suppl 2):S58-S56.

    Google Scholar 

  41. Rhode Island Department of Health, Division of Disease Control and Prevention, Office of HIV and AIDS. 2002 Rhode Island epidemiologic profile of HIV/AIDS. Available at: www.health.ri.gov/disease/communicable/hivprevention2004.pdf.

  42. 2002 Census Data for Rhode Island Methadone Programs, State of Rhode Island Division of Behavioral Healthcare Services, Substance Abuse Treatment and Prevention Services. January 2003. Available by contacting: www.mhrh.state.ri.us/substance_abuse.htm.

  43. Burris S, Lurie P, Ng M. Harm reduction in the health care system: the legality of prescribing and dispensing syringes to drug users. Health Matrix. 2001;11:5–64. Updated analysis available on-line at: http://www.temple.edu/lawschool/aidspolicy/default.htm.

    CAS  PubMed  Google Scholar 

  44. Gleghorn AA, Gee G, Vlahov D. Pharmacists’ attitudes about pharmacy sales of needles/syringes and needle exchange programs in a city without needle/syringe prescription laws. J Acquir Immune Defic Syndr Hum Retrovirol. 1998;18(suppl 1):S89-S93.

    PubMed  Google Scholar 

  45. The United States Conference of Mayors, HIV/AIDS Program. The role of pharmacies in preventing HIV among injection drug users. AIDS Information Exchange. December 1999;1–11.

  46. Friedmann PD, McCullough DM, Saitz R. Screening and intervention for illicit drug abuse: a national survey of primary care physicians and psychiatrists. Arch Int Med. 2001;161:248–251.

    Article  CAS  Google Scholar 

  47. Rich JD, Morrow K, Cunliffe T, et al. Motivational enhancement for physicians prescribing syringes to injection drug users to prevent HIV. Paper presented at: 2001 National HIV Prevention Conference; August 12–15, 2001; Atlanta, GA. Abstract 654.

  48. Centers for Disease Control and Prevention. Incorporating HIV Prevention into the medical care of persons living with HIV, July 18, 2003;52:1–24.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Josiah D. Rich MD, MPH.

Additional information

while the research was being conducted, Mr. Wolf was with the Department of Infectious Disease at The Miriam Hospital; Ms. Mehrotra is with Brown University School of Medicine; and Dr. Stein is with the School of Medicine, Department of Community Health at Brown University and HIV Services at Rhode Island Hospital; all affiliations are in Providence, Rhode Island.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rich, J.D., McKenzie, M., Macalino, G.E. et al. A syringe prescription program to prevent infectious disease and improve health of injection drug users. J Urban Health 81, 122–134 (2004). https://doi.org/10.1093/jurban/jth092

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1093/jurban/jth092

Keywords

Navigation