Skip to main content

Advertisement

Log in

Balancing the risks: Vector control and pesticide use in response to emerging illness

  • Special Feature: West Nile Virus: Public Health Issues Raised by an Emerging Illness
  • Published:
Journal of Urban Health Aims and scope Submit manuscript

Abstract

The competing public health concerns of vector-borne disease and vector control strategies, particularly pesticide use, are inherently subjective and difficult to balance. Disease response decisions must frequently be made in the absence of data or clear criteria. The factors to be weighed include the vector control measures versus those posed by the disease itself; short-term versus long-term disease management goals, specifically with regard to the issue of pesticide resistance; the need to distinguish among diseases of differing severity in making response choices; and the issue of pesticide efficacy. New York City's experience with West Nile virus has illustrated each of these issues. A framework for assessing the appropriate response to West Nile virus can serve to guide our response to likely new pathogens.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Reigart JR, Roberts JR.Recognition and Management of Pesticide Poisonings. Washington, DC: US Environmental Protection Agency; 1999, 735-R-98-003.

    Google Scholar 

  2. Mostashari F, Poshni I, Edwin B, et al. Serosurveys for West Nile infection—New York and Connecticut counties, 2000.MMWR Morb Mortal Wkly Rep. 2001;50:37–39.

    Google Scholar 

  3. New York State Department of Health. New York State West Nile virus response plan. September 2000. Available at: http://www.health.state.ny.us/nysdoh/westnile/final.htm. Accessed: October 2, 2000.

  4. Lenormand T, Bourguet D, Guillemaud T, Raymond M. Tracking the evolution of insecticide resistance in the mosquitoCulex pipiens.Nature. 1999;400:861–864.

    Article  PubMed  CAS  Google Scholar 

  5. Sukontason K, Olson JK, Hartberg WK, Duhrkopf RE. Organophosphate and pyrethroid susceptibilities ofCulex salinarius adults from Texas and New Jersey.J Am Mosquito Control Assoc. 1998;14:477–480.

    CAS  Google Scholar 

  6. Bisset J, Rodriguez M, Soca A, Pasteur N, Raymond M. Cross-resistance to pyrethroid and organophosphorus insecticides in the southern house mosquito (Diptera: Culicidae) from Cuba.J Med Entomol. 1997;34(2):244–246.

    PubMed  CAS  Google Scholar 

  7. Wirth MC, Georghiou GP. Organophosphate resistance inCulex pipiens from Cyprus.J Am Mosquito Control Assoc. 1996;12(1):112–118.

    CAS  Google Scholar 

  8. Rawlins SC, Wan JOH. Resistance in some Caribbean populations ofAedes aegypti to several insecticides.J Am Mosquito Control Assoc. 1995;11(1):59–65.

    CAS  Google Scholar 

  9. Mekuria Y, Williams DC, Hyatt MG, Zack RE, Gwinn TA. Malathion resistance in mosquitoes from Charleston and Georgetown counties of coastal South Carolina.J Am Mosquito Control Assoc. 1994;10(1):56–63.

    CAS  Google Scholar 

  10. Gubler DJ. Resurgent vector-borne diseases as a global health problem.Emerg Infect Dis. 1998;4:442–450.

    Article  PubMed  CAS  Google Scholar 

  11. Deibel R, Srihongse S, Woodall JP. Arboviruses in New York State.Am J Trop Med Hyg. 1979;28:577–582. See also Centers for Disease Control Web site, available at: www.cdc.govncidod/dvbid/arbor/arbocase.htm.

    PubMed  CAS  Google Scholar 

  12. Cernescu C, Nedela N, Tardel G, Tsai TF. Continued transmission of West Nile virus to humans in Southeastern Romania, 1997–1998.J Infect Dis. 2000;181:710–712.

    Article  PubMed  CAS  Google Scholar 

  13. Castle T, Amador M, Rawlins S, Figueroa JP, Reiter P. Absence of impact of aerial malathion treatment onAedes aegypti during a dengue outbreak in Kingston, Jamaica.Pan Am J Public Health. 1999;5(2):100–104.

    CAS  Google Scholar 

  14. Newton EAC, Reiter P. A model of the transmission of dengue fever with an evaluation of the impact of ultra-low volume (ULV) insecticide applications on dengue epidemics.Am J Trop Med Hyg. 1992;47(6):709–720.

    PubMed  CAS  Google Scholar 

  15. Perich MJ, Tidwell MA, Williams DC, et al. Comparison of ground and aerial ultra-low volume applications of malathion againstAedes aegypti in Santo Domingo, Dominican Republic.J Am Mosquito Control Assoc. 1990;6(1):1–6.

    CAS  Google Scholar 

  16. Gubler DJ.Aedes aegypti andAedes aegypti-borne disease control in the 1990s: top down or bottom up.Am J Trop Med Hyg. 1989,40(6):571–578.

    PubMed  CAS  Google Scholar 

  17. Thier A.The Toxic Treadmill. Albany, NY: Environmental Advocates and the New York Public Interest Research Group; 2000.

    Google Scholar 

  18. Blondell, J. Epidemiology of pesticide poisonings in the United States, with special reference to occupational cases.Occup Med State of the Art Rev. 1997;12(2):209–221.

    CAS  Google Scholar 

  19. Shafey O, Sekereke HJ, Hughes BJ, Heber S, Hunter RG, Brooks RG. Surveillance for acute pesticide-related illness during the medfly eradication program—Florida, 1998.MMWR Morb Mortal Wkly Rep. 1999;48:1015–1027.

    Google Scholar 

  20. National Research Council.Pesticides in the Diets of Infants and Children. Washington, DC: National Academy Press; 1993.

    Google Scholar 

  21. Fan A. 1998 malathion literature review. Memorandum from Anna M. Fan, PhD, Chief, Pesticide and Environmental Toxicology Section to Richard Kreutzer, MD, Chief Environmental Health Investigations Branch, Department of Health Services, California Environmental Protection Agency; June 26, 1998.

  22. State of California Department of Health Services.Health Risk Assessment of Aerial Application of Malathion-Bait. Berkeley, CA: State of California Dept of Health Services; 1991.

    Google Scholar 

  23. Desi I, Varga L, Farkas I. Studies on the immunosuppressive effect of organochlorine and organophosphoric insecticides in subacute experiments.J Hyg Epidemiol Microbiol Immunol. 1978;1:115–122.

    Google Scholar 

  24. Contreras HR, Bustos-Obregon E. Morphological alterations in mouse testis by a single dose of malathion.J Exp Zool. 1999;284(3):355–359.

    Article  PubMed  CAS  Google Scholar 

  25. Balasubramanian K, Vijayan AP, Ananthanarayanan P, Balasubramanian A. Effect of malathion on the testis of male albino rats.Med Sci Res. 1987;15:229–230.

    CAS  Google Scholar 

  26. Wyttenbach CR, Thompson SC. The effects of the organophosphate insecticide malathion on very young chick embryos: malformations detected by histological examination.Am J Anat. 1985;174:187–202.

    Article  PubMed  CAS  Google Scholar 

  27. Rupa DS, Reddy PP, Sreemannarayana K, Reddi OS. Frequency of sister-chromatid exchange in peripheral lymphocytes of male pesticide applicators.Environ Mol Mutagen. 1991;18:136–138.

    Article  PubMed  CAS  Google Scholar 

  28. New Jersey Department of Health and Senior Services.Hazardous Substances Fact Sheet: Malathion. Trenton, NJ: New Jersey Dept of Health and Senior Services; 1997.

    Google Scholar 

  29. Thomas DC, Petitti DB, Goldhaber M, Swan SH, Rappaport EB, Hertz-Picciotto I. Reproductive outcomes in relation to malathion spraying in the San Francisco Bay area, 1981–1982.Epidemiology. 1992;3:32–39.

    Article  PubMed  CAS  Google Scholar 

  30. Johnson K. Scientist differs with EPA on malathion.New York Times. August 18, 2000: B3.

  31. Extension Toxicology Network.Pesticide Information Profile: Malathion. Corvallis: Oregon State University; 1996.

    Google Scholar 

  32. Reigart JR, Roberts JR:Recognition and Management of Pesticide Poisonings. Washington, DC: US Environmental Protection Agency; 1999. EPA 735-R-98-003.

    Google Scholar 

  33. O'Malley M. Clinical evaluation of pesticide exposure and poisonings.Lancet. 1997; 349:1161–1166.

    Article  PubMed  Google Scholar 

  34. Muller-Mohnssen H. Chronic sequelae and irreversible injuries following acute pyrethroid intoxication.Toxicol Lett. 1999;197:161–175.

    Article  Google Scholar 

  35. Diel F, Horr B, Borck H, Savtchenko H, Mitsche T, Diel E. Pyrethroids and piperonylbutoxide affect human T-lymphocytes in vitro.Toxicol Lett. 1999;107:65–74.

    Article  PubMed  CAS  Google Scholar 

  36. Stiller-Winkler R, Hadnagy W, Leng G, Straube E, Idel H. Immunological parameters in humans exposed to pesticides in the agricultural environment.Toxicol Lett. 1999; 107:219–224.

    Article  PubMed  CAS  Google Scholar 

  37. Go V, Garey J, Wolff MS, Pogo BG. Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line.Environ Health Perspect. 1999; 107(3):173–177.

    Article  PubMed  CAS  Google Scholar 

  38. Eil C, Nisula BC. The binding properties of pyrethroids to human skin fibroblast androgen receptors and to sex hormone binding globulin.J Steroid Biochem. 1990;35:409–414.

    Article  PubMed  CAS  Google Scholar 

  39. Extension Toxicology Network.Pesticide Information Profile: Resmethrin. Corvallis: Oregon State University; 1996.

    Google Scholar 

  40. Kegley S, Neumeister L, Martin T.Disturbing the Balance: Ecological Impacts of Pesticides in California. San Francisco: Californians for Pesticide Reform; 1999.

    Google Scholar 

  41. Bohan P, Goldman L, Treser C. American Public Health Association. Maximizing public health protection with integrated vector control.American Journal of Public Health. 2000;91:22–23. Available at: www.apha.org/legislative/policy/index/htm. Accessed: March 29, 2001.

    Google Scholar 

References

  1. Gubler DJ. Resurgent vector-borne diseases as a global health problem.Emerg Infect Dis. 1998;4:442–450.

    Article  PubMed  CAS  Google Scholar 

  2. Centers for Disease Control and Prevention.Preventing Emerging Infectious Diseases: a Strategy for the 21st Century. Atlanta, GA: US Dept of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention; 1998.

    Google Scholar 

  3. Centers for Disease Control and Prevention.Epidemic/Epizootic West Nile Virus in the United States: Guidelines for Surveillance Prevention, and Control. Fort Collins, CO: US Dept of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention; 2000.

    Google Scholar 

  4. Schmaljohn C, Hjelle B. Hantavirus: a global disease problem.Emerg Infect Dis. 1997; 3:95–104.

    Article  PubMed  CAS  Google Scholar 

  5. Institute of Medicine.The Future of Public Health. Washington, DC: Institute of Medicine; 1988.

    Google Scholar 

  6. US Dept of Agriculture.Pest Management Practices: 1998 Summary. Washington, DC: US Dept of Agriculture; 1999.

    Google Scholar 

  7. IPM Associates, Inc.Introduction to Integrated Pest Management for Urban Landscapes. Eugene, OR: IPM Associates, Inc.; 1996.

    Google Scholar 

  8. Food Quality Protection Act of 1996, Pub L 104-170, 110 Stat 1489 (August 3, 1996).

  9. Brogdon WG, McAllister JC. Insecticide resistance and vector control.Emerg Infect Dis. 1998;4:605–613.

    Article  PubMed  CAS  Google Scholar 

  10. Gratz NG, Jany WC. What role for insecticides in vector control programs?Am J Trop Med Hyg. 1194;50:11–20.

    Google Scholar 

  11. United Nations Environmental Program, Persistent Organic Pollutants Committee.Report of the Inter-governmental Negotiating Committee for an International Legally Binding Instrument for Implementing International Action on Certain Persistent Organic Pollutants on the Work of Its Third Session. September 6–11, 1999. Geneva, Switzerland: United Nations; 1999.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Audrey Thier.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thier, A. Balancing the risks: Vector control and pesticide use in response to emerging illness. J Urban Health 78, 372–381 (2001). https://doi.org/10.1093/jurban/78.2.372

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1093/jurban/78.2.372

Keywords

Navigation