Herpes simplex encephalitis presenting with exclusively frontal lobe involvement
The authors report a patient with herpes simplex encephalitis who presented with magnetic resonance imaging (MRI) lesions exclusively in the frontal lobes, including the bilateral anterior cingulate gyri. She is making a good recovery after therapy with intravenous acyclovir. A similar presentation with a fatal outcome was previously reported by Rose et al (Neurology 42: 1809–1812, 1992). MRI shows temporal lesions in most patients with herpes simplex encephalitis, whereas occasional patients have normal imaging. A high index of suspicion for the diagnosis of herpes simplex encephalitis should be maintained when a patient presents with fever and brain lesions involving extratemporal limbic system structures.
Keywordscingulate gyrus encephalitis frontal lobe herpes simplex virus
Unable to display preview. Download preview PDF.
- Mekan SF, Wasay M, Khelaeni B, Saeed Z, Hassan A, Sheerani M (2005). Herpes simplex encephalitis: analysis of 68 cases from a tertiary care hospital in Karachi, Pakistan. JPak Med Assoc 55: 146–148.Google Scholar