Australasian Plant Pathology

, Volume 35, Issue 6, pp 605–618 | Cite as

Transgenic gene silencing strategies for virus control

  • R. G. DietzgenEmail author
  • N. Mitter


Co-suppression of transgenes and their homologous viral sequences by RNA silencing is a powerful strategy for achieving high-level virus resistance in plants. This review provides a brief overview of RNA silencing mechanisms in plants and discusses important transgene construct design features underpinning successful RNA silencing-mediated transgenic virus control. Application of those strategies to protect horticultural and field crops from virus infection and results of field tests are also provided. The effectiveness and stability of RNA-mediated transgenic resistance are assessed taking into account effects of viral, plant and environmental factors.

Additional keywords

double-stranded RNA RNA interference silencing suppressors small interfering RNA transgenic crops 


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Copyright information

© Australasian Plant Pathology Society 2006

Authors and Affiliations

  1. 1.Department of Primary Industries and Fisheries, Emerging Technologies, Queensland Agricultural Biotechnology CentreQueensland Bioscience PrecinctSt LuciaAustralia
  2. 2.Cooperative Research Centre for Tropical Plant ProtectionThe University of QueenslandSt LuciaAustralia

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