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A cis,fac-[RuCl2(DMSO)3(H2O)] complex exhibits ultrafast photochemical aquation/rearrangement

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Abstract

It is known that both cis,fac-[RuCl2(DMSO)3(H2O)] (1a) and trans,cis,cis-[RuCl2(DMSO)2(H2O)2] (2a) complexes, which are formed on the dissolution of trans and cis-isomers of [RuCl2(DMSO)4] in water, demonstrate light-induced anticancer activity. The first stage of 1a photochemistry is its transformation to 2a occurring with a rather high quantum yield, 0.64 ± 0.17. The mechanism of the 1a → 2a phototransformation was studied by means of nanosecond laser flash photolysis and ultrafast pump–probe spectroscopy. The reaction occurs in the picosecond time range via the formation and decay of two successive intermediates interpreted as Ru(ii) complexes with different sets of ligands. A tentative mechanism of phototransformation is proposed.

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Acknowledgments

This work has been supported by the Russian Foundation of Basic Research (Grant Number 18-33-00009).

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Authors and Affiliations

  1. Voevodsky Institute of Chemical Kinetics and Combustion, 3 Institutskaya Str., 630090, Novosibirsk, Russian Federation

    Svetlana G. Matveeva, Anton A. Shushakov, Ivan P. Pozdnyakov, Vjacheslav P. Grivin, Victor F. Plyusnin & Evgeni M. Glebov

  2. Novosibirsk State University, 2 Pirogova Str., 630090, Novosibirsk, Russian Federation

    Anton A. Shushakov, Ivan P. Pozdnyakov, Vjacheslav P. Grivin, Victor F. Plyusnin, Danila B. Vasilchenko, Andrei V. Zadesenets & Evgeni M. Glebov

  3. Nikolaev Institute of Inorganic Chemistry, 5 Lavrentyev Prosp., 630090, Novosibirsk, Russian Federation

    Danila B. Vasilchenko & Andrei V. Zadesenets

  4. Institute of Spectroscopy, Russian Academy of Sciences, 5 Fizicheskaya Str., 119333, Troitsk, Moscow, Russian Federation

    Alexei A. Melnikov & Sergei V. Chekalin

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  1. Svetlana G. Matveeva
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  2. Anton A. Shushakov
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  3. Ivan P. Pozdnyakov
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  6. Danila B. Vasilchenko
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  8. Alexei A. Melnikov
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  9. Sergei V. Chekalin
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  10. Evgeni M. Glebov
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Correspondence to Svetlana G. Matveeva, Danila B. Vasilchenko or Alexei A. Melnikov.

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Matveeva, S.G., Shushakov, A.A., Pozdnyakov, I.P. et al. A cis,fac-[RuCl2(DMSO)3(H2O)] complex exhibits ultrafast photochemical aquation/rearrangement. Photochem Photobiol Sci 17, 1222–1228 (2018). https://doi.org/10.1039/c8pp00232k

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