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A facile method to in situ fabricate three dimensional gold nanoparticle micropatterns in a cell-resistant hydrogel

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Abstract

A facile method for in situ fabrication of three-dimensional gold nanoparticle micropatterns in a cell-resistant polyethylene glycol hydrogel has been developed by combining photochemical synthesis of gold nanoparticles with photolithography technology. The gold nanoparticle micropatterns were further bio-modified with cell integrated polypeptide NcysBRGD based on a gold-thiol bond to improve cell behaviors. Primary cell tests showed that NcysBRGD can enhance cell adhesion very well on the surface of gold nanoparticle micropatterns.

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Correspondence to Yuan-Di Zhao.

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Yao, MH., Yang, J., Zhao, DH. et al. A facile method to in situ fabricate three dimensional gold nanoparticle micropatterns in a cell-resistant hydrogel. Photochem Photobiol Sci 15, 181–186 (2016). https://doi.org/10.1039/c5pp00426h

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  • DOI: https://doi.org/10.1039/c5pp00426h

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