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Figure 8 | Scientific Reports

Figure 8

From: Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages activation and enrichment, and ameliorates brain injury

Figure 8

SQ29548 protects against tMCAO-induced cerebral injury.

(A) Cresyl violet staining of brain sections from mice administered DMSO or SQ29548 at 3 d or 7 d after tMCAO (n = 4 each group). Dash line indicates infarct area. (B) Quantification of infarct volumes. (C) Neurological scores of DMSO- or SQ29548-treated mice at 3 d and 7 d after tMCAO (n = 8 each group). Values are the mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001.

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