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Figure 4 | Scientific Reports

Figure 4

From: Thromboxane A2 receptor antagonist SQ29548 reduces ischemic stroke-induced microglia/macrophages activation and enrichment, and ameliorates brain injury

Figure 4

SQ29548 inhibits microglia/macrophages activation after tMCAO injury.

mRNA levels of M1 markers CD16 (A) and CD86 (B) and M2 markers Arg-1 (C) and Ym-1 (D) in the ipsilateral striatum of sham-PBS (n = 4), tMCAO-DMSO (n = 8) and tMCAO-SQ29548 (n = 8) groups at 3 d, 7 d following tMCAO. Values are the mean ± SEM. *P < 0.05, **P < 0.01.

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