Abstract
Pelvic lymph node involvement is an adverse prognostic factor in clinically localized prostate cancer, and a knowledge of nodal status is important for patient management. Whereas nodal disease has been widely regarded as incurable, evidence is now accumulating that some men with lymph node involvement may benefit from radical multimodality treatment approaches. Pelvic nodal status may be assessed by predictive nomograms, by imaging studies and by surgery. The pros and cons of each method are discussed together with the prospects for future development. Optimal strategies combining the different diagnostic approaches for the detection of lymph node metastases are considered in the context of the changing therapeutic implications of nodal disease.
Similar content being viewed by others
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Parker, C., Husband, J. & Dearnaley, D. Lymph node staging in clinically localized prostate cancer. Prostate Cancer Prostatic Dis 2, 191–199 (1999). https://doi.org/10.1038/sj.pcan.4500311
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.pcan.4500311
- Springer Nature Limited
Keywords
This article is cited by
-
PSA density versus risk stratification for lymphadenectomy-making decision in patients with prostate cancer undergoing radical prostatectomy
International Urology and Nephrology (2011)