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Psychiatric disorders in Wolfram syndrome heterozygotes

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Abstract

Wolfram syndrome is an autosomal recessive disorder caused by a gene on the short arm of chromosome 4 and characterized by a range of neurological, psychiatric and behavioural abnormalities. Recent research suggests that heterozygous carriers of the disease gene are at increased risk of psychiatric hospitalization.

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  1. Neuroscience Genetics Unit, Tenovus Building, University of Wales College of Medicine, Heath Park, Cardiff, CF4 4XN, UK

    M J Owen

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  1. M J Owen
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Owen, M. Psychiatric disorders in Wolfram syndrome heterozygotes. Mol Psychiatry 3, 12–13 (1998). https://doi.org/10.1038/sj.mp.4000349

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