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Puzzles of psychiatric genetics—new candidate gene approaches

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Abstract

Bipolar disorder and schizophrenia may show ‘anticipation,’ or earlier age-of-onset in successive generations within a pedigree, suggesting that triplet repeat expansion mutations could play a causative role in these disorders. This genetic hypothesis can be tested using a candidate gene approach.

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Authors and Affiliations

  1. Department of Psychiatry, Johns Hopkins University School of Medicine, 720 Rutland Ave, Baltimore, 21205-2196, MD, US

    C A Ross & R L Margolis

  2. Department of Neuroscience, Johns Hopkins University School of Medicine, 720 Rutland Ave, Baltimore, 21205-2196, MD, US

    C A Ross

  3. Program in Cellular and Molecular Medicine, Johns Hopkins University School of Medicine, 720 Rutland Ave, Baltimore, 21205-2196, MD, US

    C A Ross

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  1. C A Ross
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  2. R L Margolis
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Ross, C., Margolis, R. Puzzles of psychiatric genetics—new candidate gene approaches. Mol Psychiatry 2, 432–433 (1997). https://doi.org/10.1038/sj.mp.4000339

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  • DOI: https://doi.org/10.1038/sj.mp.4000339

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