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Thymidine kinase 1 – A prognostic and diagnostic indicator in ALL and AML patients

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References

  1. Kantarjian HM . Adult acute lymphocytic leukemia: critical review of current knowledge. Am J Med 1994; 97: 176–184.

    Article  CAS  PubMed  Google Scholar 

  2. O'Neill KL, Buckwalter MR, Murray BK . Thymidine kinase: diagnostic and prognostic potential. Expert Rev Mol Diagn 2001; 1: 428–433.

    Article  CAS  PubMed  Google Scholar 

  3. Hannigan BM, Barnett YA, Armstrong DB, McKelvey-Martin VJ, McKenna PG . Thymidine kinases: the enzymes and their clinical usefulness. Cancer Biother 1993; 8: 189–197.

    Article  CAS  PubMed  Google Scholar 

  4. Sherley JL, Kelly TJ . Regulation of human thymidine kinase during the cell cycle. J Biol Chem 1988; 263: 8350–8358.

    CAS  PubMed  Google Scholar 

  5. Johansson M, Karlsson A . Cloning of the cDNA and chromosome localization of the gene for human thymidine kinase 2. J Biol Chem 1997; 272: 8454–8458.

    Article  CAS  PubMed  Google Scholar 

  6. Zhang J, Jia Q, Zou S, Zhang P, Zhang X, Skog S et al. Thymidine kinase 1: a proliferation marker for determining prognosis and monitoring the surgical outcome of primary bladder carcinoma patients. Oncol Rep 2006; 15: 455–461.

    Article  CAS  PubMed  Google Scholar 

  7. He Q, Zhang P, Zou L, Li H, Wang X, Zhou S et al. Concentration of thymidine kinase 1 in serum (S-TK1) is a more sensitive proliferation marker in human solid tumors than its activity. Oncol Rep 2005; 14: 1013–1019.

    CAS  PubMed  Google Scholar 

  8. Zhang F, Shao X, Li H, Robison JG, Murray BK, O'Neill KL . A monoclonal antibody specific for human thymidine kinase 1. Hybridoma 2001; 20: 25–34.

    Article  PubMed  Google Scholar 

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Acknowledgements

We thank KEM Baillie and JM Bridges for providing the serial blood samples from the ALL and AML patients. We also thank the Biological Carcinogenesis Branch for providing blood samples.

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Authors and Affiliations

  1. Department of Microbiology and Molecular Biology, Brigham Young University, Provo, UT, USA

    K L O'Neill, F Zhang, H Li, D G Fuja & B K Murray

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  1. K L O'Neill
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  2. F Zhang
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  3. H Li
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  4. D G Fuja
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Correspondence to K L O'Neill.

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O'Neill, K., Zhang, F., Li, H. et al. Thymidine kinase 1 – A prognostic and diagnostic indicator in ALL and AML patients. Leukemia 21, 560–563 (2007). https://doi.org/10.1038/sj.leu.2404536

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