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Clinical significance of TP53 mutation in myeloma

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References

  1. Vousden KH, Lu X . Live or let die: the cell's response to p53. Nat Rev Cancer 2002; 2: 594–604.

    Article  CAS  PubMed  Google Scholar 

  2. Fonseca R, Barlogie B, Bataille R, Bastard C, Bergsagel PL, Chesi M et al. Genetics and cytogenetics of multiple myeloma: a workshop report. Cancer Res 2004; 64: 1546–1558.

    Article  CAS  PubMed  Google Scholar 

  3. Fonseca R, Blood E, Rue M, Harrington D, Oken MM, Kyle RA et al. Clinical and biologic implications of recurrent genomic aberrations in myeloma. Blood 2003; 101: 4569–4575.

    Article  CAS  PubMed  Google Scholar 

  4. Greipp PR, San Miguel J, Durie BG, Crowley JJ, Barlogie B, Blade J et al. International staging system for multiple myeloma. J Clin Oncol 2005; 23: 3412–3420.

    Article  PubMed  Google Scholar 

  5. Bischoff JR, Kirn DH, Williams A, Heise C, Horn S, Muna M et al. An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science 1996; 274: 373–376.

    Article  CAS  PubMed  Google Scholar 

  6. Zhang WW, Fang X, Mazur W, French BA, Georges RN, Roth JA . High-efficiency gene transfer and high-level expression of wild-type p53 in human lung cancer cells mediated by recombinant adenovirus. Cancer Gene Ther 1994; 1: 5–13.

    PubMed  Google Scholar 

  7. Kirn D, Hermiston T, McCormick F . ONYX-015: clinical data are encouraging. Nat Med 1998; 4: 1341–1342.

    Article  CAS  PubMed  Google Scholar 

  8. Tolcher AW, Hao D, de Bono J, Miller A, Patnaik A, Hammond LA et al. Phase I, pharmacokinetic, and pharmacodynamic study of intravenously administered Ad5CMV-p53, an adenoviral vector containing the wild-type p53 gene, in patients with advanced cancer. J Clin Oncol 2006; 24: 2052–2058.

    Article  CAS  PubMed  Google Scholar 

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Chng, W., Price-Troska, T., Gonzalez-Paz, N. et al. Clinical significance of TP53 mutation in myeloma. Leukemia 21, 582–584 (2007). https://doi.org/10.1038/sj.leu.2404524

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