References
Brunning RD, Matutes E, Flandrin G, Vardiman J, Bennet J, Head D et al. Acute myeloid leukaemias and myelodysplastic syndromes, therapy related. In: Jaffe ES, Harris NL, Stein H, Vardiman JW (eds). World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC press: Lyon, 2001, pp 89–91.
Vicari AM, Ciceri F, Folli F, Lanzi R, Colombo B, Comi G et al. Acute promyelocytic leukemia following mitoxantrone as single agent for the treatment of multiple sclerosis. Leukemia 1998; 12: 441–442.
Cattaneo C, Almici C, Borlenghi E, Motta M, Rossi G . A case of acute promyelocytic leukemia following mitoxantrone treatment of multiple sclerosis. Leukemia 2003; 17: 986–987.
Beaumont M, Sanz M, Carli PM, Maloisel F, Thomas X, Detourmignies L et al. Therapy-related acute promyelocytic leukemia. J Clin Oncol 2003; 11: 2123–2137.
Novoselac AV, Reddy S, Sanmugarajah J . Acute promyelocytic leukemia in a patient with multiple sclerosis following treatment with mitoxantrone. Leukemia 2004; 18: 1561–1562.
Arruda OW, Montú MB, de Oliveira Mde S, Ramina R . Acute myeloid leukaemia induced by mitoxantrone. Arq Neuropsiquiatr 2005; 63: 327–329.
Mandelli F, Diverio D, Avvisati G, Luciano A, Barbui T, Bernasconi C et al. Molecular remission in PML/RAR alpha-positive acute promyelocytic leukemia by combined all-trans retinoic acid and idarubicin (AIDA) therapy. GIMEMA and AIEOP Cooperative Groups. Blood 1997; 90: 1014–1021.
Mistry AR, Felix CA, Whitmarsh RJ, Mason A, Reiter A, Cassinat B et al. DNA topoisomerase II in therapy-related acute promyelocytic leukemia. N Engl J Med 2005; 352: 1529–1538.
Saccardi R, Mancardi GL, Solari A, Bosi A, Bruzzi P, Di Bartolomeo P et al. Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life. Blood 2005; 105: 2601–2607.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ledda, A., Caocci, G., Spinicci, G. et al. Two new cases of acute promyelocytic leukemia following mitoxantrone treatment in patients with multiple sclerosis. Leukemia 20, 2217–2218 (2006). https://doi.org/10.1038/sj.leu.2404443
Published:
Issue Date:
DOI: https://doi.org/10.1038/sj.leu.2404443
- Springer Nature Limited
This article is cited by
-
Results from the 5-year, phase IV RENEW (Registry to Evaluate Novantrone Effects in Worsening Multiple Sclerosis) study
BMC Neurology (2013)
-
Natalizumab in aggressive multiple sclerosis after haematopoietic stem cell transplantation
Neurological Sciences (2012)
-
Acute myeloid leukemia induced by mitoxantrone treatment for aggressive multiple sclerosis
Neurological Sciences (2008)