Skip to main content
SpringerLink
Log in

Reported cryptic rearrangements of CBFβ-MYH11 in acute myeloid leukaemia are not due to false priming of contaminating DNA

  • Correspondence
  • Published:
Leukemia Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1

References

  1. Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, Harrison G, Rees J, Hann I, Stevens R, Burnett A, Goldstone A . The importance of diagnostic cytogenetics on outcome of AML: analysis of 1,612 patients entered into the MRC AML 10 trial Blood 1998 92: 2322–2333

    CAS  PubMed  Google Scholar 

  2. Liu P, Tarle SA, Hajra A, Claxton DF, Marlton P, Freedman M, Siciliano MJ, Collins FS . Fusion between transcription factor CBFβ/PEBP2β and a myosin heavy chain in acute myeloid leukemia Science 1993 261: 1041–1044

    Article  CAS  Google Scholar 

  3. Langabeer SE, Walker H, Gale RE, Wheatley K, Burnett AK, Goldstone AH, Linch DC . Frequency of CBFβ/MYH11 fusion transcripts in patients entered into the UK MRC AML trials Br J Haematol 1997 96: 736–739

    Article  CAS  Google Scholar 

  4. Poirel H, Radford-Weiss I, Rack K, Troussard X, Veil A, Valensi F, Picard F, Guesnu M, Leboeuf D, Melle J, Dreyfus F, Flandrin G, Macintyre E . Detection of the chromosome 16 CBFβ-MYH11 fusion transcript in myelomonocytic leukemias Blood 1995 85: 1313–1322

    CAS  PubMed  Google Scholar 

  5. Ritter M, Thiede C, Schackel U, Schmidt M, Alpen B, Paschenberg U, Mohr B, Ehninger G, Neubauer A . Underestimation of inversion (16) in acute myeloid leukaemia using standard cytogenetics as compared with polymerase chain reaction: results of a prospective investigation Br J Haematol 1997 98: 969–972

    Article  CAS  Google Scholar 

  6. Costello R, Sainty D, Lecine P, Cusenier A, Mozziconacci M-J, Arnoulet C, Maraninchi D, Gastaut J-A, Imbert J, Lafage-Pochitaloff M, Gabert J . Detection of CBFβ/MYH11 fusion transcripts in acute myeloid leukemia: heterogeneity of cytological and molecular characteristics Leukemia 1997 11: 644–650

    Article  CAS  Google Scholar 

  7. Wong KF, Kwong YL . Trisomy 22 in acute myeloid leukemia: a marker for myeloid leukemia with monocytic features and cytogenetically cryptic inversion 16 Cancer Genet Cytogenet 1999 109: 131–133

    Article  CAS  Google Scholar 

  8. Langabeer SE, Walker H, Rogers JR, Burnett AK . Wheatley K, Swirsky D, Goldstone AH, Linch DC, Incidence of AMLI/ETO fusion transcripts in patients entered into the MRC AML trials Br J Haematol 1997 99: 925–928

    Article  CAS  Google Scholar 

  9. Hackwell SM, Robinson DO, Harvey JF, Ross FM . Identification of false-positive CBFβ/MYH11 RT-PCR results Leukemia 1999 13: 1617–1619

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the Kay Kendall Leukaemia Fund.

Author information

Authors and Affiliations

  1. Department of Haematology, University College London Medical School, London, UK

    SE Langabeer, RE Gale, H Walker & DC Linch

Authors
  1. SE Langabeer
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. RE Gale
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H Walker
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. DC Linch
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Langabeer, S., Gale, R., Walker, H. et al. Reported cryptic rearrangements of CBFβ-MYH11 in acute myeloid leukaemia are not due to false priming of contaminating DNA. Leukemia 14, 944–945 (2000). https://doi.org/10.1038/sj.leu.2401751

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.leu.2401751

  • Springer Nature Limited

Search

Navigation