Skip to main content

Advertisement

SpringerLink
Log in

Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans

  • Expanded Abstract
  • Published:
Journal of Human Hypertension Submit manuscript

Abstract

Essential hypertension is a major risk factor for cardiovascular disease in humans, and originates from both genetic and environmental factors. Data from animal and more recently human studies have indicated the presence of a gene influencing blood pressure on human chromosome 17. This study tested for linkage of markers located on chromosome 17q to essential hypertension in African Caribbean hypertensive families. No support of linkage was found between the markers studied and hypertension, however only genes of a lamda sib value of less than 1.8 could be excluded

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Author information

Authors and Affiliations

  1. Clinical Pharmacology, St Bartholomew’s and The Royal London School of Medicine and Dentistry, London, UK

    J Knight, GTB Gardner & MJ Caulfield

  2. Chemical Endocrinology, St Bartholomew’s and The Royal London School of Medicine and Dentistry, London, UK

    AJL Clark

Authors
  1. J Knight
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. GTB Gardner
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. AJL Clark
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. MJ Caulfield
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to J Knight.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Knight, J., Gardner, G., Clark, A. et al. Investigation of chromosome 17q as a locus for human essential hypertension in African Caribbeans. J Hum Hypertens 14, 385–387 (2000). https://doi.org/10.1038/sj.jhh.1001025

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.jhh.1001025

  • Springer Nature Limited

Keywords

Search

Navigation