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Role of prostaglandins in hypertension

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Abstract

The role of prostaglandins (PGs) in hypertension (HT) is reviewed, emphasising their biochemical characteristics, physiological effects and functions, especially in the cardiovascular area, and the current evidence of their participation in the antihypertensive activity of a balanced mechanism to maintain normal blood pressure. Also, the clinical use of PGs and the future of such autacoids in the treatment of HT and other diseases or conditions is mentioned.

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Authors and Affiliations

  1. Department of Physiology, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela

    JA Colina-Chourio

  2. Department of Pharmacology, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela

    JA Colina-Chourio & RM Avila-Hernández

  3. Department of Medicine, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela

    N Godoy-Godoy

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  1. JA Colina-Chourio
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  2. N Godoy-Godoy
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  3. RM Avila-Hernández
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Colina-Chourio, J., Godoy-Godoy, N. & Avila-Hernández, R. Role of prostaglandins in hypertension. J Hum Hypertens 14 (Suppl 1), S16–S19 (2000). https://doi.org/10.1038/sj.jhh.1000981

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  • DOI: https://doi.org/10.1038/sj.jhh.1000981

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