Abstract
Objective: To determine reference values for fat-free mass index (FFMI) and fat mass index (FMI) in a large Caucasian group of apparently healthy subjects, as a function of age and gender and to develop percentile distribution for these two parameters.
Design: Cross-sectional study in which bioelectrical impedance analysis (50 kHz) was measured (using tetrapolar electrodes and cross-validated formulae by dual-energy X-ray absorptiometry in order to calculate FFMI (fat-free mass/height squared) and FMI (fat mass/height squared).
Subjects: A total of 5635 apparently healthy adults from a mixed non-randomly selected Caucasian population in Switzerland (2986 men and 2649 women), varying in age from 24 to 98 y.
Results: The median FFMI (18–34 y) were 18.9 kg/m2 in young males and 15.4 kg/m2 in young females. No difference with age in males and a modest increase in females were observed. The median FMI was 4.0 kg/m2 in males and 5.5 kg/m2 in females. From young to elderly age categories, FMI progressively rose by an average of 55% in males and 62% in females, compared to an increase in body mass index (BMI) of 9 and 19% respectively.
Conclusions: Reference intervals for FFMI and FMI could be of practical value for the clinical evaluation of a deficit in fat-free mass with or without excess fat mass (sarcopenic obesity) for a given age category, complementing the classical concept of body mass index (BMI) in a more qualitative manner. In contrast to BMI, similar reference ranges seems to be utilizable for FFMI with advancing age, in particular in men.
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Acknowledgements
We thank the Foundation Nutrition 2000 Plus for its financial support. We are indebted to the dietitians at the Geneva University Hospital for their help.
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Schutz, Y., Kyle, U. & Pichard, C. Fat-free mass index and fat mass index percentiles in Caucasians aged 18–98 y. Int J Obes 26, 953–960 (2002). https://doi.org/10.1038/sj.ijo.0802037
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DOI: https://doi.org/10.1038/sj.ijo.0802037
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