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Fetal gene therapy

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References

  1. Couzin J . RAC confronts in utero gene therapy proposals Science 1998 282: 27

    Article  CAS  Google Scholar 

  2. Coutelle C, Douar A-M, Colledge W, Froster U . The challenge of fetal gene therapy Nat Med 1995 864

  3. Senut M-C, Gage F . Prenatal gene therapy: can the technical hurdles be overcome? Mol Med Today 1999 5: 152

    Article  CAS  Google Scholar 

  4. Mickelson C . Minutes of RAC Meeting September 1998

  5. Robbins P et al. Increased probability of expression from modified retroviral vectors in embryonal stem cells and embryonal carcinoma cells J Virol 1997 71: 9466

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Porada C et al. In utero gene therapy: transfer and long-term expression of the bacterial neo(r) gene in sheep after direct injection of retroviral vectors into preimmune fetuses Hum Gene Ther 1998 9: 1571

    Article  CAS  Google Scholar 

  7. M Themis et al. Successful expression of β-galactosidase and factor IX transgenes in fetal and neonatal sheep after ultrasound-guided percutaneous adenovirus vector administration into the umbilical vein Gene Therapy 1999 6: 1239–1248

    Article  Google Scholar 

  8. Tedgard U . Carrier testing and prenatal diagnosis of haemophilia–utilisation and psychological consequences Haemophilia 1998 4: 365

    Article  CAS  Google Scholar 

  9. SK Schachtner, CA Buck, JM Bergelson, HS Baldwin . Temporally regulated expression patterns following in utero adenovirus-mediated gene transfer Gene Therapy 1999 6: 1249–1257

    Article  Google Scholar 

  10. Gene Therapy Advisory Committee . Report on the potential use of gene therapy in utero. Health Departments of the United Kingdom, November 1998 Hum Gene Ther 1999 10: 689

    Article  Google Scholar 

  11. Moulton G . Panel finds in utero gene therapy proposal is premature J Natl Cancer Inst 1999 91: 407

    Article  CAS  Google Scholar 

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  1. Rm 7101 Thurston Building, UNC Gene Therapy Center, CB#7352, Chapel Hill, 27599, NC, USA

    Christopher E Walsh MD PhD

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  1. Christopher E Walsh MD PhD
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Walsh MD PhD, C. Fetal gene therapy. Gene Ther 6, 1200–1201 (1999). https://doi.org/10.1038/sj.gt.3300991

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