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An uncommon case of late thrombotic thrombocytopenic purpura (42 months) after autologous peripheral blood stem cell (PBSC) transplantation in a child

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Abstract

Thrombotic thrombocytopenic purpura (TTP) is a serious complication following bone marrow transplantation (BMT). Therapeutic plasma exchange does not appear to be effective in its management in contrast to classical TTP. We report the case of a child with TTP 3 years after autologous PBSC transplantation, in whom remission was achieved by administration of cyclosporin A, after failure of plasmapheresis as primary treatment.

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Author notes

  1. L Madero: Correspondence: Dr L Madero, Department of Pediatrics, Bone Marrow Transplantation Unit, Hospital Infantil Niño Jesús, Avda. Menéndez Pelayo, 65, 28009 – Madrid, Spain

Authors and Affiliations

  1. Department of Pediatric Hematology and Oncology, Bone Marrow Transplantation Unit, Hospital Infantil Niño Jesús, Autonomous University of Madrid, Spain

    M González-Vicent, M A Díaz & L Madero

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  1. M González-Vicent
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  2. M A Díaz
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  3. L Madero
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González-Vicent, M., Díaz, M. & Madero, L. An uncommon case of late thrombotic thrombocytopenic purpura (42 months) after autologous peripheral blood stem cell (PBSC) transplantation in a child. Bone Marrow Transplant 23, 735–736 (1999). https://doi.org/10.1038/sj.bmt.1701649

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  • DOI: https://doi.org/10.1038/sj.bmt.1701649

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