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Hyperbaric oxygen therapy in a case of post-total body irradiation colitis

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Abstract

We report a 21-year-old man who experienced symptoms of colitis following autologous TBI-conditioned PBSC transplantation, which persisted despite conventional treatment. Abdominal echography showed a thickened, stratified wall of the cecum, of the right colon and of part of the transverse colon. Hyperbaric oxygen therapy (20 sessions of 100% oxygen inhalation at 2.5 bar for 120 min in a hyperbaric chamber) achieved a prompt clinical recovery as well as complete disappearance of the ultrasound abnormalities.

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Authors and Affiliations

  1. Bone Marrow Transplant Unit, Institute of Pediatrics, University of Pisa, Italy

    C Favre, A Ventura, M Nardi, M Massimetti, F Papineschi & P Macchia

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  1. C Favre
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  2. A Ventura
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  3. M Nardi
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  4. M Massimetti
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  5. F Papineschi
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  6. P Macchia
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Favre, C., Ventura, A., Nardi, M. et al. Hyperbaric oxygen therapy in a case of post-total body irradiation colitis. Bone Marrow Transplant 21, 519–520 (1998). https://doi.org/10.1038/sj.bmt.1701114

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  • DOI: https://doi.org/10.1038/sj.bmt.1701114

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